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Braz. j. med. biol. res ; 37(11): 1623-1630, Nov. 2004. ilus, tab
Artigo em Inglês | LILACS | ID: lil-385881

RESUMO

The objective of the present study was to assess esophageal motor function in 21 children (7.5 ± 2.9 years) with caustic strictures. Esophageal manometry was performed using a water-infusion system interfaced with a polygraph and displayed on a computer screen. The data were compared with those obtained from 9 healthy children. Radionuclide transit was determined by studying deglutition of a single bolus of 99mTc pertechnetate in 10 ml of water. Non-peristaltic low-amplitude and long-duration waves were the most common findings detected in patients with strictures longer than 20 percent of esophageal length (N = 11). Compared with the control group, these patients presented lower mean amplitude and longer mean duration of waves (24.4 ± 11.2 vs 97.9 ± 23.7 mmHg, P < 0.05, and 6.7 ± 2.4 vs 1.6 ± 0.1 s, P < 0.05, respectively). Six patients presented low-amplitude waves just below the constricted site. Ten children presented delayed esophageal transit. There was an association between dysphagia and abnormalities on manometry (P = 0.02) and between symptoms and scintigraphy data (P = 0.01). Dysphagia in caustic strictures is due to esophageal motility abnormalities, which are closely related to the scarred segment.


Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Queimaduras Químicas/fisiopatologia , Transtornos da Motilidade Esofágica/induzido quimicamente , Estenose Esofágica/induzido quimicamente , Hidróxido de Sódio/toxicidade , Queimaduras Químicas/etiologia , Transtornos da Motilidade Esofágica/fisiopatologia , Transtornos da Motilidade Esofágica , Estenose Esofágica/fisiopatologia , Estenose Esofágica , Manometria/métodos , Índice de Gravidade de Doença
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