RESUMO
Abstract Artocarpus altilis (Parkinson ex F.A.Zorn.) Fosberg, Moraceae, is a native tree of Southeast Asia introduced to South America at the beginning of the 19th century. It has been used by several indigenous communities. This paper aims to preserve the traditional knowledge at risk of loss and to validate some of the applications found. Current ancestral practices were documented, by interviews in a scarcely contacted Amazonic Kichwa community from the Bobonaza River (Ecuador). The findings were compared with bibliographic citations from other Amazonian cultures. A bioinformatics literature survey of articles that report experiments on the chemical constituents was executed. The major findings are that some uses given in this population may be considered surprising, but the molecular profile of this species justifies its local value. It has cycloartenol (terpenoid), artoindonesianin F (stilbenoid), and different groups of flavonoids (chalcones, prenylflavones, oxepinoflavones, pyrano-flavones, xanthones). This information can prove effective in a search for novel drugs, focused to merge potential innovative uses of the plant.