Time-course of health-related adaptations in response to combined training in hypertensive elderly: immune and autonomic modulation interactions

This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Methods: The patients will be randomized to a control or combined training group interventions (aerobic and resistance exercise), with monthly assessments in four months. Although, the changes in baseline blood pressure is the primary clinical outcome, the secondary outcomes include: body composition, cardiorespiratory fitness, muscle strength, arterial stiffness, baroreceptor sensitivity, cardiovascular autonomic modulation, inflammatory markers, oxidative stress, growth factors, tissue remodeling markers, metabolic profile, renal function, cognitive function and quality of life. Results: To support the understanding of the blood pressure changes in hypertensive elderly, a time-course of exercise-induced adaptations including cardiovascular and immunological adaptations are fundamental for research in this field. Conclusion: To investigate the time-course of combined training-induced adaptations including all the diverse aspects of health in hypertensive elderly a well-controlled protocol design is necessary, mainly to clarify the relationship between cardiovascular and immunological exercise-induced adaptations.(AU)

Efeito do treinamento com pesos sobre a flexibilidade de homens de meia-idade / Effect of weight training on the flexibility of middle-aged men

O presente estudo teve como objetivo investigar o efeito de 12 semanas de treinamento com pesos (TP) na flexibilidade de homens de meia-idade. Possivelmente, indivíduos na meia-idade sedentários apresentem melhoras na flexibilidade somente com a realização de TP. Foram selecionados 16 indivíduos de meia-idade (48,8 ± 5,0 anos) divididos aleatoriamente em dois grupos: grupo controle (GC, n=8) e grupo treinamento (GT, n=8). O GT realizou TP duas vezes por semana, em dias não consecutivos (3 séries de 15 repetições, 1 minuto de pausa). A flexibilidade de ombro, tronco, quadril e joelhos foram aferidas bilateralmente (com exceção do tronco) antes e após o período experimental. Não foi verificado efeito do tempo para nenhuma das variáveis analisadas (p>0,05). O TP de baixa intensidade não reduz a flexibilidade de homens de meia-idade.

The aim of the present study was to investigate the effect of 12 weeks of resistance training on flexibility levels of middle-aged men. Possibly, middle-aged sedentary subjects might show flexibility improvements only performing resistance training. Sixteen middle-aged men (48.8 ± 5.0 years) were selected for the present study. They were randomly divided in two groups: control group (GC, n=8) and training group (GT, n=8). The GT performed resistance training twice a week, in alternate days (3 sets of 15 repetitions, with 1 minute rest between sets). Shoulder, trunk, hips and knees flexibility were assessed bilaterally (with the exception of trunk) pre- and post- study period. No significant time interaction was found for any variable (p>0.05). Low-intensity resistance training does not reduce middle-aged men flexibility.