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1.
Gut and Liver ; : 452-456, 2012.
Artigo em Inglês | WPRIM | ID: wpr-58003

RESUMO

BACKGROUND/AIMS: This study assessed the efficacy of a rifaximin plus levofloxacin-based rescue regimen in patients that had failed both triple and quadruple standard regimens for the eradication of Helicobacter pylori. METHODS: We treated patients for H. pylori between August 2009 and April 2011. The triple regimen consisted of combined treatment with amoxicillin, clarithromycin, and pantoprazole for 1 week. For failed cases, a quadruple regimen of tetracycline, metronidazole, bismuth dicitrate, and lansoprazole for 1 week was administered. The rescue regimen for persistently refractory cases was rifaximin 200 mg t.i.d., levofloxacin 500 mg q.d., and lansoprazole 15 mg b.i.d. for 1 week. RESULTS: In total, 482 patients were enrolled in this study. The eradication rates associated with the first and second regimens were 58% and 60%, respectively. Forty-seven out of 58 patients who failed with the second-line regimen received rifaximin plus levofloxacin-based third-line therapy. The eradication rate for the third regimen was 65%. The cumulative eradication rates were 58%, 85%, and 96% for each regimen, respectively. CONCLUSIONS: A rifaximin plus levofloxacin-based regimen could be an alternative rescue therapy in patients with resistance to both triple and quadruple regimens for the eradication of H. pylori.


Assuntos
Humanos , 2-Piridinilmetilsulfinilbenzimidazóis , Amoxicilina , Bismuto , Claritromicina , Helicobacter , Helicobacter pylori , Metronidazol , Ofloxacino , Rifamicinas , Tetraciclina
2.
Korean Journal of Medicine ; : 588-594, 2011.
Artigo em Coreano | WPRIM | ID: wpr-68584

RESUMO

Pulmonary alveolar proteinosis (PAP) is a rare condition that is treated using whole lung lavage. A recent study suggested that granulocyte-macrophage colony stimulating factor (GM-CSF) plays roles in both the pathogenesis and treatment of PAP. We present a 69-year-old man with PAP who deteriorated despite bilateral whole lung lavage; that said, his symptoms, chest X-ray findings, and pulmonary function test improved after GM-CSF inhalation therapy over 12 months. GM-CSF therapy is an effective treatment modality for PAP.


Assuntos
Idoso , Humanos , Lavagem Broncoalveolar , Fatores Estimuladores de Colônias , Fator Estimulador de Colônias de Granulócitos e Macrófagos , Inalação , Pulmão , Proteinose Alveolar Pulmonar , Testes de Função Respiratória , Terapia Respiratória , Tórax
3.
Artigo em Coreano | WPRIM | ID: wpr-194421

RESUMO

X-linked agammaglobulinemia is a common type of primary immunodeficiency disorder that's caused by mutation of the BTK gene. The absence of B lymphocytes and plasma cells causes recurrent infections. Patients with X-linked agammaglobulinemia also have a high risk for developing hematological malignancies and, to a lesser degree, carcinoma. We report here on a 26-years-old male patient who suffered with X-linked agammaglobulinemia that was caused by BTK gene mutation, and he developed a gastric cancer in the antrum. He was noted to have chronic atrophic gastritis and diffuse intestinal metaplasia on the endoscopic examination that was done 7 years previously. We recommend regular esophagogastroduodenoscopic evaluation for a patient with X-linked agammaglobulinemia in order to make an early diagnosis of stomach carcinoma.


Assuntos
Humanos , Masculino , Adenocarcinoma , Agamaglobulinemia , Linfócitos B , Diagnóstico Precoce , Gastrite Atrófica , Doenças Genéticas Ligadas ao Cromossomo X , Neoplasias Hematológicas , Metaplasia , Plasmócitos , Estômago , Neoplasias Gástricas
4.
Artigo em Inglês | WPRIM | ID: wpr-45987

RESUMO

Idiopathic proximal hemimegacolon is a disorder characterized by bowel dilatation proximal to the splenic flexure. It is a very rare and therefore a poorly understood clinical entity. This report describes a case of idiopathic proximal hemimegacolon in a 44-year-old woman. The patient suffered from 2 episodes of constipation and bowel dilatation over 4 years and was successfully treated by medical therapy.


Assuntos
Adulto , Feminino , Humanos , Colo Transverso , Constipação Intestinal , Dilatação , Futilidade Médica
5.
Artigo em Inglês | WPRIM | ID: wpr-27391

RESUMO

Deglutition syncope is a situational syncope that is diagnosed only by a detailed history. We report deglutition syncope in a 62-year-old man, who had permanent atrial fibrillation. The patient had no structural or functional abnormalities of the esophagus. During syncopal attacks, his electrocardiography showed ventricular asystole that was sustained for 12 seconds. The patient was successfully treated by implantation of a permanent pacemaker.


Assuntos
Humanos , Pessoa de Meia-Idade , Fibrilação Atrial , Deglutição , Eletrocardiografia , Esôfago , Parada Cardíaca , Síncope
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