A Study for Causative Diseases of Globus Pharyngeus Patients Who Have NoPathologic Conditions in Laryngopharynx / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Globus pharyngeus is the feeling of a lump or foreign body in the throat. Otolaryngologists are often confronted with this condition, and some authors report that it represents 3 percent of all new clinic referrals. Unfortunately, we still do not completely understand the etiologies of globus pharyngeus, but there are recently increasing evidences to link the globus symptoms with various diseases. MATERIAL AND METHODS: We selected 32 globus patients, who exhibited no pathologic condition in physical examinations, and were analysed by general work up, barium esophagogram, 24 hour-ambulatory double-probe pH monitoring, esophageal manometry test, Fuchs' series, and MMPI. RESULTS: The results were as follows, gastroesophago-laryngopharyngeal reflux disease (n=15: 46.9%), various psychotic problems (n=11: 34.4%), esophageal motility disorders (n=7: 21.9%), duodenal ulcer (n=2: 6.3%), Eagle's syndrome (n=2: 6.3%), and hiatal hernia (n=1: 3.1%). In 5 cases, we couldn't find the etiology of globus pharyngeus. CONCLUSION: Globus pharyngeus patients, who had no pathologic findings in layrnx and pharynx, might have laryngopharyngeal-gastroesophageal reflux diseases and psychologic problems.

A Case of Maxillary Sinus Involvement in Multiple Myeloma / 대한이비인후과학회지

Multiple myeloma is a neoplasm of mature and immature plasma cells. Extraosseous tissues are involved frequently in multiple myeloma. The most common sites of involvement are spleen, liver, lymph nodes, and kidneys. Sinus involvement of multiple myeloma is rare but usually presents in secondary extramedullary plasmacytoma. Primary extramedullary plasmacytoma is neoplastic proliferation of plasmacytes in reticuloendothelial tissues and occurs most commonly in head and neck areas. Evaluation of the extent of disease is essential for proper management of this patient. The treatment and prognosis are different according to whether the extramedullary plasmacytoma is primary or secondary. Recently, we experienced a case of multiple myeloma which simultaneously progressed in maxillary sinus in spite of systemic chemotherapy and report with literature review.