RESUMO
OBJECTIVE: To promote the rational use of antibiotics.METHODS: A retrospectively analysis was conducted on the application of antibiotics in 4 186 discharge case histories in 2005.RESULTS: Of the total 4 186 cases,the application rate of antibiotics was 64.48%,among which,56.17% were prophylactic use of antibiotics and 5.89% used antibiotics without indication.The consumption of antibiotics occupied 45.90% of the total medicines consumed.The nosocomial infection rate was 4.16%,of which,23.56% were fungous infections.The incidence of adverse drug reactions was 2.56%.CONCLUSION: The rate for the prophylactic use of antibiotics in our hospital is on the high side,which may result in high incidences of drug resistant strains and nosocomial infections,therefore,measures should taken to tight the control of the administration of antibiotics.