Case-control study on relationship between diet quality and thyroid nodules / 环境与职业医学

Background Both domestic and foreign studies on the diet quality of patients with thyroid nodules are rare at present, and the relationship between thyroid nodules and diet quality is still unclear. Objective This study aims to evaluate the diet quality of thyroid nodules with the China Healthy Diet Index (CHDI) and to explore the relationship between diet quality and thyroid nodules. Methods We conducted a hospital-based case-control study in which 387 patients with thyroid nodules were matched individually (1∶1) by gender and age (±3 years) to the controls who ordered a routine physical examine and with negative thyroid nodules reported by B-ultrasound in the same hospital. A structured questionnaire was applied to collect data on general characteristics and diet. CHDI was employed to evaluate the diet quality of the two groups. CHDI is based on the Dietary Guidelines for Chinese Residents and the recommended food intake in the balanced diet pagoda, combined with the dietary nutritional status of Chinese population. The index contains 13 scoring components, and the highest total score is 100, with a higher score representing better dietary quality. CHDI scores < 60, 60-<80, and ≥80 are recognized as unqualified, qualified, and good diet quality, respectively. Results The scores of the thyroid nodule cases were lower than the scores of the controls in total vegetables, dark vegetables, fruits, and fish/shrimps (all Ps<0.05). The nonparametric test results found that there were significant differences in the distributions of scores in total vegetables, dark vegetables, fruits, soybeans, and fish/shrimps between the case and the control groups (all Ps<0.05). The percentages reaching the full scores in food variety, meat and eggs, and empty calories in both groups exceeded 60%, while the percentages reaching the full scores in whole grains/beans/tubers, dairy, soybeans, and sodium were lower than 30% in the two groups. The median CHDI scores of the thyroid nodule cases and the controls were 69.1 and 72.9, respectively; the cases' CHDI score was lower than the controls' (P<0.05). The proportions of unqualified diet in the case and the control groups accounted for 23.0% and 13.7% respectively (P=0.001). After being adjusted for education level, marital status, occupation, monthly household income per capita, body mass index, hypertension/diabetes, energy, and iodine intake, the results of logistic regression analysis showed that the risk for thyroid nodules was negatively associated with CHDI score (CHDI qualified group vs. CHDI unqualified group, OR=0.484, 95%CI: 0.291-0.804; CHDI good dietary quality group vs. CHDI unqualified group, OR=0.414, 95%CI: 0.230−0.746). Conclusion The diet quality of patients with thyroid nodules is lower than that of the control group, as the former reported lower consumptions of total vegetables, dark vegetables, fruits, and fish/shrimps. Those who have good or qualified diet quality show a reduced risk of thyroid nodules than those with unqualified dietary quality.

Case-control study on association of female reproductive factors with risk of papillary thyroid cancer / 环境与职业医学

Background Papillary thyroid cancer is the result of a variety of pathogenic factors. The prevalence of papillary thyroid cancer varies greatly in different regions, and the disease is more harmful to women. Objective This study aims to explore the relationship between reproductive factors and papillary thyroid cancer, and to provide basic data for prevention and control of the disease. Methods A 1∶1 age (±3 years) matched case-control study was conducted in 331 pairs of newly confirmed papillary thyroid cancer cases and controls from two hospitals in Shanghai from November 2012 to December 2013. Comparisons were made in the history of menstruation, pregnancy, gynecological and breast diseases, and other variables between the two groups. Results The results of univariate analysis indicated that the proportions of education below bachelor degree, married, and mainly manual workers in the case group were significantly higher than those in the control group (P<0.05); the proportion of those with a family history of thyroid diseases in the case group was significantly higher than that in the control group (P<0.05); the proportions of the cases with irregular menstruation (77.34%), a history of using oral contraceptive or hormone drugs (24.77%), a history of benign gynecological diseases (31.72%), and a history of gynecological surgery (9.67%) were significantly higher than the proportions in the control group (P<0.05). After adjusting potential confounding factors such as history of CT examination, age, kinds of family salt, total iodine intake every day, education level, occupation, marital status, body mass index, and family history of thyroid diseases, the results of multiple logistic regression analysis showed that irregular menstruation (OR=1.767, 95%CI: 1.122-2.782; P=0.014), surgical menopause (OR=12.787, 95%CI: 3.202-51.057; P<0.001), pregnancy >1 time (OR =2.490, 95%CI: 1.196-5.184; P=0.015), and the history of using oral contraceptive or hormone drugs (OR=2.389, 95%CI: 1.338-4.268; P=0.003) were the risk factors of papillary thyroid cancer. Conclusion Irregular menstruation, surgical menopause, history of pregnancy, and history of using oral contraceptive or hormone drugs might be the risk factors of papillary thyroid cancer. To reduce the incidence of papillary thyroid cancer, strengthened health education and rational use of contraceptives are recommended.

Dairy product intake and influencing factors in residents of Shanghai / 中华流行病学杂志

Objective To understand the dairy product intake in residents of Shanghai,its seasonal changes and the influencing factors.Methods A group of representative residents was surveyed and followed up in four seasons in Shanghai during 2012-2014.Information of the dairy product intake was collected by food frequency questionnaire.Results Liquid milk and yogurt were the main dairy products consumed by the residents of Shanghai.The annual dairy product intake rate was 41.8％,and the median of dairy intake of milk was 145.3 g/d,accounting for 48.4％ of reference dietary intake value,and only 4.5％ of people's diary product intake reached intake reference value.The area specific differences in intake rate of liquid milk,yogurt and total dairy product intake were significant in four seasons and in whole year (P＜0.05).The area specific differences in total dairy product intake were significant (P＜0.05) in spring,summer and winter.In general,it was shown that dairy product intake in urban area was higher than that in suburban area and in rural area.The data of Shanghai and urban area showed that the total dairy product intake was significant different among four seasons (P＜0.05),but no significant difference was observed among four seasons in suburban and rural areas.The logistic regression analysis results showed that people with average household income higher than local average level or higher education levels were more likely to consume dairy products daily.People who reported to have good health status or sleep quality were more likely to drink milk compared to those who have worse health status or sleep quality (P＜0.05).Conclusions Even though dairy product intake rate and volume have been improved in residents in Shanghai,it is still stay at lower level,especially in rural area.To promote consumption of dairy products,it is necessary to control diary product price from macro perspective,and strengthen healthy education about the importance of dairy product intake and guide residents to select suitable dairy products.

Dietary pattern and its seasonal characteristic in residents of Shanghai, 2012-2014 / 中华流行病学杂志

Objective To analyze dietary pattern and its seasonal characteristic in residents of Shanghai.Methods A representative sample was surveyed and followed up in four different seasons during 2012-2014.Information of food consumption was collected by 3-day 24-hour dietary recall and condiments weighing method.The intake of energy and macronutrients were calculated according to the Chinese Food Composition Table.Results Annual average daily intake was 191.09 g for grain,250.69 g for vegetable,107.23 g for fruit,223.53 g for animal food,96.39 g for dairy products,11.19 g for soy bean and its product,36.54 g for cooking oil,and 7.57 g for salt.Significant differences were observed in food consumption among different seasons (P＜0.05).Annual average daily intake of energy was 2 048.70 kcal,carbohydrates was 241.04 g,protein was 82.35 g,fat was 85.99 g and proportion of energy contributed by fat was 37.99％.Different seasons,age,residential areas,and income were influence factors for food consumption (P＜0.05).Conclusions Energy intake was adequate in residents of Shanghai.Unhealthy dietary pattem,including high proportion of fat and consumption of cooking oil and salt (lower than average intake of large cities,but higher than recommendation),was observed.It is necessary to take appropriate nutrition intervention,and future researches on dietary intake should consider seasonal influences.

General plan of Shanghai Diet and Health Survey / 中华流行病学杂志

Shanghai Diet and Health Survey (SDHS) was designed to prospectively access local residents' food consumption,energy and nutrient intake,related chemical contaminant exposure,and the seasonal change trend to explore the relationship of diet with health.Data from SDHS can be used as fundamental information and scientific evidences for the development of local nutrition and food safety policies.

Dairy product intake and influencing factors in residents of Shanghai / 中华流行病学杂志

Objective To understand the dairy product intake in residents of Shanghai,its seasonal changes and the influencing factors.Methods A group of representative residents was surveyed and followed up in four seasons in Shanghai during 2012-2014.Information of the dairy product intake was collected by food frequency questionnaire.Results Liquid milk and yogurt were the main dairy products consumed by the residents of Shanghai.The annual dairy product intake rate was 41.8％,and the median of dairy intake of milk was 145.3 g/d,accounting for 48.4％ of reference dietary intake value,and only 4.5％ of people's diary product intake reached intake reference value.The area specific differences in intake rate of liquid milk,yogurt and total dairy product intake were significant in four seasons and in whole year (P＜0.05).The area specific differences in total dairy product intake were significant (P＜0.05) in spring,summer and winter.In general,it was shown that dairy product intake in urban area was higher than that in suburban area and in rural area.The data of Shanghai and urban area showed that the total dairy product intake was significant different among four seasons (P＜0.05),but no significant difference was observed among four seasons in suburban and rural areas.The logistic regression analysis results showed that people with average household income higher than local average level or higher education levels were more likely to consume dairy products daily.People who reported to have good health status or sleep quality were more likely to drink milk compared to those who have worse health status or sleep quality (P＜0.05).Conclusions Even though dairy product intake rate and volume have been improved in residents in Shanghai,it is still stay at lower level,especially in rural area.To promote consumption of dairy products,it is necessary to control diary product price from macro perspective,and strengthen healthy education about the importance of dairy product intake and guide residents to select suitable dairy products.

Dietary pattern and its seasonal characteristic in residents of Shanghai, 2012-2014 / 中华流行病学杂志

Objective To analyze dietary pattern and its seasonal characteristic in residents of Shanghai.Methods A representative sample was surveyed and followed up in four different seasons during 2012-2014.Information of food consumption was collected by 3-day 24-hour dietary recall and condiments weighing method.The intake of energy and macronutrients were calculated according to the Chinese Food Composition Table.Results Annual average daily intake was 191.09 g for grain,250.69 g for vegetable,107.23 g for fruit,223.53 g for animal food,96.39 g for dairy products,11.19 g for soy bean and its product,36.54 g for cooking oil,and 7.57 g for salt.Significant differences were observed in food consumption among different seasons (P＜0.05).Annual average daily intake of energy was 2 048.70 kcal,carbohydrates was 241.04 g,protein was 82.35 g,fat was 85.99 g and proportion of energy contributed by fat was 37.99％.Different seasons,age,residential areas,and income were influence factors for food consumption (P＜0.05).Conclusions Energy intake was adequate in residents of Shanghai.Unhealthy dietary pattem,including high proportion of fat and consumption of cooking oil and salt (lower than average intake of large cities,but higher than recommendation),was observed.It is necessary to take appropriate nutrition intervention,and future researches on dietary intake should consider seasonal influences.

General plan of Shanghai Diet and Health Survey / 中华流行病学杂志

Shanghai Diet and Health Survey (SDHS) was designed to prospectively access local residents' food consumption,energy and nutrient intake,related chemical contaminant exposure,and the seasonal change trend to explore the relationship of diet with health.Data from SDHS can be used as fundamental information and scientific evidences for the development of local nutrition and food safety policies.

Correlation Study of Peak Enhancement and Shift Time at Peak between Normal Pancreas and Abdominal Aorta / 中国医学影像学杂志

Purpose To explore the correlation between normal pancreas and abdominal aorta in the peak enhancement (PE) and the shift time at the peak by applying the multislices spiral CT perfusion imaging.Materials and Methods Prospectively analyzed 62 patients who received enhancement CT examination for the superior or the middle abdomen,underwent optimum level CT perfusion imaging after plain scanning.These data were processed on a Vitreal 2.0 worker-station by using Toshiba body software package.The time-density curves (TDC) of the normal pancreas and the abdominal aorta were drawn,the PE and the shift time of PE were recorded and their correlation was analyzed.Results Compared with abdominal aorta,the mean value of PE of the normal pancreas was lower,and the difference was statistically significant [(111.94± 14.42)HU vs (351.83 ± 74.93)HU,P＜0.05],the mean difference was (246.10± 65.86)HU.Compared with abdominal aorta,the mean shift times of PE of the normal pancreas was latter,and the difference was statistically significant [(37.56±6.90) s vs (30.82±6.73) s,P＜0.05],the mean difference was (6.54±2.97)s.The PE and shift time of PE of the normal pancreas were positively and linearly correlated with that of abdominal aorta (r=0.438,r=0.379).Conclusion The PE of the normal pancreas is not synchronous with that of the abdominal aorta.The shift time of the former is usually 6～8 seconds slower than that of the latter.This provides a basis to find the PE of the normal pancreas in enhanced scan.