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Artigo | IMSEAR | ID: sea-221016

RESUMO

INTRODUCTION: Dengue infection is a major health problem worldwide including our country.Globally the incidence of Dengue has grown dramatically in the recent years. Every year during themonsoon months and later, many parts of the country witness outbreak of dengue infection. 2020was no exception and we experienced an outbreak of this vector borne disease in Bhuj. An analysisof these patients revealed that in addition to the classical features of fever, body ache, rash andthrombocytopenia and bleeding tendency, there were other features such as liver dysfunctionincluding a preferential rise of SGOT, hepatomegaly, splenomegaly, ascites, gallbladder wall edemaand pericholecystic fluid collection.OBJECTIVE: To study clinical, biochemical and radiological changes in the liver of patients withDengue fever.METHOD:observational and cross-sectional study was conducted on a 50 suspected cases of Dengue feveradmitted and diagnosed at GKGH hospital Bhuj in October 2020. Detailed history, clinicalexamination, biochemical parameters, radiological investigation for liver function was done in allpatients. All patients were treated as per NVBDCP guidelines.RESULTS: all patients in our study had hepatic dysfunction in the form of elevated SGOT abovenormal limits.CONCLUSIONS: Our study shows that there are certain features of Dengue that are not known tobe usually associated with it. The presence of raised liver enzymes in all patients (SGOT > SGPT),ascites, hepatomegaly, splenomegaly, and gallbladder edema and pericholecystic fluid collection.

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