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1.
Indian J Pathol Microbiol ; 2003 Oct; 46(4): 621-4
Artigo em Inglês | IMSEAR | ID: sea-75883

RESUMO

431 patients with thrombosis of different venous system were evaluated for underlying acquired and inherited prothrombotic states. Associated acquired risk factors were observed to be present in 28.7% patients and possible inherited in 32.3%, in the rest, no cause could be identified. Major acquired risk factors included coexistence of liver disease (12.2%), oral contraceptives (4.1%), puerperium (2.5%), malignancy (2.3%) and lupus anticoagulant (2%). Low levels of protein C were detected in 21.1% and of which 11.3% were attributed to acquired factors. Protein S deficiency was found in 19.0% and of these 10.4% cases were associated with acquired risk factors. Antithrombin III (AT III) deficiency was detected in 6.4% of patients, of which 4.8% were secondary to acquired factors. In the rest, deficiency of protein C, protein S and AT III were attributed to inherited factors as no associated acquired risk factor was present. Activated protein C resistance (APC-R) was present in 12.5% cases.


Assuntos
Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Deficiência de Antitrombina III/complicações , Criança , Anticoncepcionais Orais/efeitos adversos , Feminino , Humanos , Índia , Hepatopatias/complicações , Masculino , Pessoa de Meia-Idade , Gravidez , Complicações na Gravidez/etiologia , Deficiência de Proteína C/complicações , Deficiência de Proteína S/complicações , Fatores de Risco , Trombose Venosa/sangue
2.
Indian J Pediatr ; 2000 Sep; 67(9): 635-46
Artigo em Inglês | IMSEAR | ID: sea-81633

RESUMO

Guillian Barré Syndrome (GBS) is an acquired disease of the peripheral nerves that is characterized clinically by rapidly progressing paralysis, areflexia, and albumino-cytological dissociation. It affects both genders, involves people of all ages, is reported worldwide, and in the post-polio era, it is the most common cause of an acute generalized paralysis. The clinical features are distinct and a history and an examination generally lead to a high suspicion of the diagnosis that can then be confirmed by supportive laboratory tests and electrodiagnostic studies. This review discusses the recent advances in understanding of the different variants of GBS such as acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor sensory axonal neuropathy (AMSAN), and the Fisher syndrome. The clinical, electrodiagnostic criteria, immunopathogenesis, and management of GBS and its variants are discussed.


Assuntos
Diagnóstico Diferencial , Eletrodiagnóstico , Eletrofisiologia , Síndrome de Guillain-Barré/classificação , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Síndrome de Miller Fisher/diagnóstico , Prognóstico
3.
Indian J Pediatr ; 1995 Jul-Aug; 62(4): 467-71
Artigo em Inglês | IMSEAR | ID: sea-83123

RESUMO

The coping and adaptation of 39 children (6-12 years) to Acute Lymphoblastic Leukemia was studied during the first remission with a projective technique--Children's Apperception Test (CAT-S). Seventy seven percent of the children gave adequate responses. Among these, disease awareness was present in 96%, expectation of a favourable outcome was held by 70%, though 61% evidenced emotional distress. Children's psychiatric morbidity was found to be associated with non-response to CAT-S, to anxiety related themes, and negatively with ability to maintain an expectation of a positive outcome.


Assuntos
Adaptação Psicológica , Distribuição de Qui-Quadrado , Criança , Feminino , Humanos , Índia , Masculino , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico , Qualidade de Vida
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