RESUMO
Thirty Patients of Histologically confirmed endometrial carcinoma admitted and treated over a period of three years in the department of obstetrics and Gynecology Govt Medical College Jammu, were studied to evaluate the risk factors in endometrial Carcinoma. The major risk factors in this study were hyperinsulinemia, hypertension, obesity and increasing age. Hyperinsulinemia has a potential role in growth and development of endometrial carcinoma, as insulin, in postmenopausal women with endometrial carcinoma, leads to increased stromal secretion of androstenedione which gets aromatized to form unbound oestradiol, having proliferative action on endometrium. The other risk factors noted in the study were early menarche, heavy menstrual flow, late menopause and diabetes. Since most of the risk factors are associated with hyperinsulinemia and insulin resistance, hyperinsulinemia can act as a good clinical marker in patients of endometrial carcinoma.
RESUMO
A total of 40 cases of total body cancer (TBC) reported at District Hospital. Doda between 1st January, 2002 to 31st December, 2002. ENT cancers comprised 23 (57.5%) cases. Carcinoma of the oesophagus was the commonest cancer amongst TBC comprising of 7 (17.5%) cases followed by carcinoma breast and thyroid comprising of 5 (12.5%) cases each, carcinoma of skin and lymphoma comprising of 4 (10%) cases each. Commonest age group involved was 4060 years. ENT cancers constituted the major burden of TBC in District Doda.
RESUMO
A case with bony metastasis to right femur from a primary carcinoma of gall bladder is described. This is probably one of the most rare presentation of the disease without producing any signs or symptoms suggestive of a primary pathology in gall bladder.