RESUMO
The compounds containing heterocyclic moiety played an important role in the field of medicine and agriculture. It makes possible research upgrading the synthesis, modification and changes in structure of heterocyclic compounds. The pyrazolines have their own importance in heterocyclic compounds due to valuable biological activities. The chemistry of chalcones has generated a lot of scientific studies with special reference to biological applications such as anti-ulcer, antitumour, antitubercular, antidepressant and fungicidal activities. Literature survey indicates that pyrazolines have not been prepared from sulfamino and ethereal linkaging containing chalcones. In the present work para-methoxy benzenesulphonil chloride reacts with metaminoacetophenone to form 3[4'-methoxybenzenesulfonamido] acetophenone [I]. In second step acetophenone [I] reacts with different aromatic aldehyde to form chalcones [II a-c]. In third step chalcones are cyclized with hydrazine hydrate, phenylhydrazine and 2,4-dinitrophenyl hydrazine to form new substituted-2-pyrazolinesI[1-16]. The structures of newly synthesized compounds are confirmed by elemental analysis, IR and p-NMR spectral studies. The synthesized compounds are screened for their anthelmintic activity