Anti-inflammatory Effect of Lycopene on Chronic Bacterial Prostatitis Rat Model / 대한비뇨기과학회지

PURPOSE: Chronic bacterial prostatitis (CBP) is the most common urological disease in adult males, with antibiotic therapy being the gold standard for its treatment. However, long-term therapy results in many side effects as well as bacterial resistance. For these reasons, there is a need for a new treatment modality to replace traditional antibiotic therapy. Lycopene, an extract of tomatoes, has antioxidant effects against various bacteria and synergistic effects with antibiotics. We evaluate the synergistic effects of lycopene on the treatment of CBP in an animal model. MATERIALS AND METHODS: Forty five rats demonstrating CBP were randomly divided into 4 groups; the control, lycopene, ciprofloxacin and lycopene with ciprofloxacin groups. All drug treatments were conducted over a period of 2 weeks. After treatment, the results were analyzed, with the microbiological cultures and histological findings of the prostate and urine samples compared with the control group and between each group. RESULTS: The uses of ciprofloxacin, and lycopene with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in prostatic inflammation compared with the control group (p<0.05). The lycopene with ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvements in prostatic inflammation compared with the ciprofloxacin group (p<0.05). CONCLUSIONS: These results suggest that lycopene may be an effective material in the treatment of CBP. Especially, the combination treatment of lycopene and ciprofloxacin has synergistic effects. Therefore, it is suggest that the combination of lycopene and ciprofloxacin may be effective in the treatment of CBP, and with a higher success rate.

Expandable Metallic Stent Placement for Nutcracker Syndrome / 대한비뇨기과학회지

Herein, a new left renal vein stenting procedure (expandable metallic stent placement), which provided relief for an 18-year-old man incapacitated by an intermittent gross hematuria, is reported. The placement of an expandable metallic stent is a minimally invasive therapy, and a simpler and more physiological therapy than previous approaches to Nutcracker syndrome.

Laparoscopic Radical Cystectomy with Orthotopic Ileal W-neobladder / 대한비뇨기과학회지

We report our initial experience with laparoscopic radical cystectomy of an orthotopic neobladder. A 68 years old male patient with muscle invasive, organ confined, and transitional cell carcinoma of the bladder underwent operation. The operation specimen was extracted through the 5 cm sized, muscle splitting incision in the umbilical trocar site. The urinary diversion was achieved by ileal W-neobladder through a removal site of a specimen. The orthotopic neobladder was sutured to the urethra intracorporeally. Operation time and blood loss were 11 hours and 450 ml, respectively. The patient was discharged on the 14th postoperative day. Laparoscopic radical cystectomy, which involves the orthotopic neobladder creation, is feasible, although difficult and technically demanding. With growing experience, laparoscopic radical cystectomy can be an alternative to open technique.

Intrascrotal Extratesticular Epidermal Cyst / 대한비뇨기과학회지

An epidermal cyst, presenting as an intrascrotal tumor, with no relation to the testicles or cord structures, is a rare benign tumor. Their etiology is unknown, but the most widely accepted theory on the histogenesis of testicular epidermal cysts is that they are the end result of a monolayer teratoma arising from germ cells; however, an extratesticular epidermoid cyst is believed to be an abnormal closure of the median raphe and urethral groove. An extratesticular epidermal cyst is normally subcutaneous, and can be localized anywhere along the median raphe, from the distal penis to the anus. To our knowledge, there has been no case reported in the Korean literature. A case of an intrascrotal epidermal cyst is reported in a 44-year-old man.