RESUMO
Giant fibroadenomas are benign tumors, but their rapid growth and large size together with their rarity may determine difficulties in the clinical approach. The authors present 2 cases of giant juvenile fibroadenoma of the breast in girls aged 14 and 16 years, and the respective diagnostic workup and conservative surgical treatment. The diagnosis was made on fine needle aspiration cytology which was confirmed on histopathology. These tumours are almost always benign and should be treated with breast conserving surgery.
RESUMO
We report the case of a 19-year old boy presenting in the emergency with severe epigastric pain whose biochemical tests revealed elevated serum amylase and lipase levels and a clinical diagnosis of acute pancreatitis was made. On ultrasonic examination, the pancreas appeared bulky with a linear tubular echogenic worm (ascaris) seen within the prominent main pancreatic duct. Successful removal of the pancreatic duct worm was achieved through endoscopic retrograde cholangio pancreatography (ERCP).
Assuntos
Adulto , Ascaríase/cirurgia , Colangiopancreatografia Retrógrada Endoscópica , Humanos , Masculino , Ductos Pancreáticos/diagnóstico por imagem , Pancreatite/parasitologiaRESUMO
The Papillon-Lefevre syndrome is a rare genetic disorder with a predisposition to severe infections. We describe Papillon-Lefevre syndrome in a 17 year old boy from a family where four out of eight siblings were affected with this disease and who presented with recurrent pyogenic liver abscesses over a period of 9 years, an association never previously reported.
Assuntos
Adolescente , Humanos , Abscesso Hepático/complicações , Masculino , Doença de Papillon-Lefevre/genéticaRESUMO
An efficient plant regeneration system was developed for two important Indian chickpea cultivars, C-235 and HC-1. Immature cotyledons (7-8 mm) directly formed shoots without an intervening callus phase on MS medium containing B5 vitamins, BAP (2.0 mg/l), IBA (0.125 mg/l), AgNO3 (1.69 mg/l) and phytagel (2.5 g/l). The regenerated shoots had normal morphology and were successfully rooted in half strength MS medium under partial dark conditions. Regenerated plants were transferred to potted soil. However, the survival rate of pot house transferred plants was 17.6 per cent.
Assuntos
Cicer/crescimento & desenvolvimentoRESUMO
Pancreatic adenocarcinoma can present with a vast spectrum of rare manifestations. It usually occurs after the age of 50 years, the peak incidence being in sixth and seventh decades. We report a previously asymptomatic subject of pancreatic adenocarcinoma who presented for the first time with massive upper gastrointestinal hemorrhage. Endoscopy revealed ruptured esophageal varices which were secondary to tumour-induced thrombosis of the portal vein. Besides the uncommon mode of presentation, the patient was unusual because of his young age. Further, he was non-icteric at the time of presentation and remained so throughout the clinical course despite having a large lesion in the head of the pancreas.
Assuntos
Adenocarcinoma/complicações , Adulto , Varizes Esofágicas e Gástricas/etiologia , Hemorragia Gastrointestinal/etiologia , Humanos , Masculino , Neoplasias Pancreáticas/complicações , Veia Porta , Trombose Venosa/etiologiaRESUMO
Granulomatous mediastinitis is a rare condition, and tuberculosis and fungal infections are the most important causes of this potentially lethal condition. Tuberculous mediastinitis usually presents with fever, cough, dyspnoea and rarely, florid features of obstruction to intra-thoracic structures are seen. A case of tuberculous mediastinitis presenting as a suprasternal lump, a rare presentation, is described here.
Assuntos
Granuloma/diagnóstico , Humanos , Masculino , Mediastinite/diagnóstico , Pessoa de Meia-Idade , Esterno/patologia , Tuberculose Pulmonar/diagnósticoRESUMO
We report a patient with an infected hepatic hydatid cyst, which spontaneously ruptured into the inferior vena cava, with resultant thrombosis of the inferior vena cava, and left renal, right common iliac and right external iliac veins.
Assuntos
Adulto , Diagnóstico Diferencial , Equinococose Hepática/complicações , Humanos , Masculino , Ruptura Espontânea , Tomografia Computadorizada por Raios X , Veia Cava Inferior , Trombose Venosa/etiologiaRESUMO
In pediatric age group, rectal bleeding is both common and distressing. Unlike in adults, very few studies comparing diagnostic efficacy of double contrast barium enema (DCBE) and Colonoscopy are available in children. A prospective study was performed to compare the diagnostic accuracy of high quality DCBE against colonoscopy in children with overt rectal bleeding. Fourty four children underwent flexible colonoscopy and DCBE independently. The final diagnosis was made after considering all investigations. Against this gold standard, the sensitivity and specificity of DCBE were 66.66% and 100% while that of colonoscopy 74.35% and 100% respectively. When assessing polypoidal lesions of colon, diagnostic yield of enema study was 86.20% as compared to 72.41% with colonoscopy. In colitis cases, the similar figures for enema and endoscopy were 53.84% and 76.92% respectively. The observed differences were statistically insignificant. No significant preparation, premedication or procedure related complications were encountered. The study thus highlights the utility and complementary role of DCBE and colonoscopy for evaluation of children with rectal bleeding.
Assuntos
Sulfato de Bário/diagnóstico , Criança , Pré-Escolar , Colonoscopia , Meios de Contraste , Enema , Hemorragia Gastrointestinal/diagnóstico , Humanos , Lactente , Valor Preditivo dos Testes , Estudos Prospectivos , Doenças Retais/diagnóstico , Sensibilidade e EspecificidadeRESUMO
Seventy-seven clinically normal children with kidneys of normal size were examined sonographically. Renal parenchymal volumes were calculated and related to age, height, body weight and body surface area; growth charts were constructed. A significant correlation was found between the renal parenchymal volume and the body somatometric parameters. The present report thus provides norms for renal parenchymal volume in Indian children.
Assuntos
Antropometria , Constituição Corporal , Criança , Pré-Escolar , Feminino , Humanos , Índia , Lactente , Rim/crescimento & desenvolvimento , Masculino , Valores de Referência , Análise de RegressãoRESUMO
Forty patients of histologically proven esophageal carcinoma were subjected to computed tomography (CT) with the objective to assess its reliability in preoperative evaluation of these patients. The findings were confirmed on surgery in twenty five of these patients, thought to be resectable. Bronchoscopy was performed to evaluate bronchial tree in cases of tumor of upper and middle third of esophagus. CT was found to be sensitive in predicting the location and size of tumor, in assessing invasion of tracheo-bronchial tree, spread to liver, celiac and left gastric nodes. However, it was not successful in picking up metastatic spread to local periesophageal nodes in five cases and celiac in one case. The study concluded CT should be carried out for preoperative evaluation of esophageal carcinoma to select operable cases and avoid unnecessary radicle surgery in advanced cases.
Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias Esofágicas/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
Fifty preterm newborn infants with gestational age of 28-36 weeks were subjected to real time cranial sonography to (a) evaluate the ventricular system and brain parenchyma, (b) determine the incidence of intracranial abnormalities, and (c) to establish the utility and advantages of routine cranial sonography in preterm infants. The lateral ventricular width varied from 6-12 mm (8.67 +/- 1.85 mm) while hemispheric width ranged between 3.68 to 3.95 cm with a mean of 3.84 +/- 0.25 cm. The lateral ventricular ratio ranged from 20.9 to 26.4% and it showed progressive decrease with increasing gestational age. Cavum septum pellucidum was found in 68% of the preterms. Incidental intracranial pathologies were detected in 12% of the preterms screened.
Assuntos
Antropometria/métodos , Encefalopatias/diagnóstico por imagem , Cefalometria/métodos , Ecoencefalografia/métodos , Feminino , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Doenças do Prematuro/diagnóstico por imagem , Masculino , Crânio/diagnóstico por imagemAssuntos
Anormalidades Congênitas/diagnóstico , Ecocardiografia Doppler , Estudos de Avaliação como Assunto , Feminino , Doenças Fetais/diagnóstico , Cardiopatias Congênitas/diagnóstico , Humanos , Recém-Nascido , Imageamento por Ressonância Magnética , Gravidez , Tomografia Computadorizada por Raios X , Ultrassonografia Pré-NatalRESUMO
Six term newborns, presenting with seizures, in whom cranial sonogram showed isolated periventricular hemorrhage (SEH) are described. Age of onset of seizures ranged from day one of birth to day twenty-one. Seizures appeared spontaneously in previously healthy newborns in three cases. All but one survived, and three have near normal development. Isolation of hemorrhage to the periventricular area suggests germinal matrix to be the source of hemorrhage in these cases. These cases also emphasize the need to consider diagnosis of IVH in term-newborns presenting with seizures.