1.
Journal of Xi'an Jiaotong University(Medical Sciences)
;
(6)1982.
Artigo
em Chinês
| WPRIM
| ID: wpr-535004
RESUMO
Total flavones of hippophase rhamnoides (TFH) inhibited the contraction of isolated rabbit aortic preparations induced by KCl, CaCl_2 and noradrenaline (NE), shifted the dose-response curvesto the right and depressed the maximal response. PD_2' values were 5.79, 5.75 and 5.81 respectively. TFH could also reduce Ca~(2+) -dependent contraction in rabbit aortic preparations. These results suggest that relaxation of vascular smooth muscles caused by TFH may be due to TFH natagonistic effect on transmembrane Ca~(2+) channels.