Preliminary Results of Donor Action in Korea / 대한이식학회지

BACKGROUND: Donor Action (DA) is a well-known program used to evaluate the potential of organ donors and to survey hospital attitudes toward organ donation in a region or nation. DA has not yet been fully implemented in Korea. METHODS: We collected medical information on expired patients from 9 hospitals in Yeoung-nam province. We also passed out Hospital Attitude Survey questionnaires in those same 9 hospitals. We reviewed the medical records of the expired patients in the neurological and neurosurgical critical care units from January 1, 2009 to December 31, 2009. Data was analyzed with a DA system database. RESULTS: A total of 704 patients were enrolled. Altogether, 307 patients (43.6%) were potential donors, and 26 patients (6.5%) were reported to an to organ procurement organization. Among the potential donors, a family approach was taken with 33 patients (10.7%), and family consent was obtained in 26 cases (8.5%). Organ donation was done with 24 patients (7.8%). Among the potential donors, 88.6% of them were not identified as potential donors. Hospital attitude surveys were given to 417 hospital staff members. A positive attitude towards organ donation was shown in 85%. However, only 55.4% of hospital staff agreed on the concept of brain death. CONCLUSIONS: Among the processes of organ donation, identifying a potential donor is a critical step to increase organ donation.

Study for the Relationship between the Post-Transplant Renal Function and the Donor Score Using Deceased Donor Scoring System / 대한이식학회지

BACKGROUND: Due to the shortage of kidney donation, deceased donor kidney from the expended criteria donor has been used as an alternative. For this, deceased donor scoring system was suggested by Nyberg and his colleagues. We evaluated the Nyberg's scores with 77 patients who received deceased donor kidney. METHODS: We reviewed the records of 77 patients who received deceased-donor kidney transplantation between January, 1, 2003 and Augst, 31, 2008 in Pusan,Paik hospital. Renal function was estimated by Cockroft-Gault equation at 6 month, 1 year, 2 year after transplantation and creatinine reduction ratio on post-transplant day 2 (CRR2). RESULTS: The mean age of deceased donor was 41.1+/-10.4 (male: n=55; female: n=22) and the mean last eGFR before procurement was 72.6+/-4 and HLA mismatching was 3.46+/-1.4. Renal function at 6 months was associated with donor age and last eGFR before procurement. Deceased donor score was ranged from 2 to 26. The number of each grade using the score system by Nyberg et al was 18 in A, 39 in B, 19 in C. The score showed negative correlation with eGFR at 6 months, 1 year and 2 years (P<0.05), but the R-square values were low. There were significant differences between group A+B and C in CRR2 and eGFR at 2 years. CONCLUSIONS: This study showed that donor age is the most important factor in the deceased donor scoring system.