Thyroid and lipid profile in chronic kidney disease in Southern India

Background: The progression of chronic kidney disease(CKD) is linked to a multitude of comorbidities, such as thyroid dysfunction, dyslipidemia, and cardiovascular disease. Objective were to determinethe thyroid and serum lipid profile of CKD patients and to establish correlation between severity of renal disease with these 2metabolic parameters.Methods: This was a prospective study conducted among the 100 CKD patients over 1 year admitted in the department of urology and nephrology at our hospital. Results: There were 66 (66%) male patients and 36 (36%)female patients among the 100 patients. There were no patients in grade 1, whereas there were 2, 20, 66, and 12 patients in grades 2-5 CKD, respectively. In each grade of CKD, the mean age, eGFR, urea, creatinine, thyroid profile, and lipid profile were computed individually. The levels of urea, creatinine, and eGFR differed significantly across CKD grades 2-5. The thyroid profile differed significantly across CKD grades 2-5. The lipid profile differed significantly across CKD grades 2-5, with p=0.000, >0.05, 0.000, >0.05, >0.05 for total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) levels, respectively.Conclusions: The number of patients increases with decreasing T3 and T4 and increasing thyroid stimulating hormone (TSH) proportionate to the severity of the renal failure. In addition, hypothyroidism is becoming more common in people with chronic renal disease. Serum triglycerides, LDL, and VLDL levels rise statistically significantly in CKD grades 3-5 patients.

Practices of contraception among rural people in Nellore district, Andhra Pradesh: a cross-sectional study

Background: As per the census 2011, the provisional population of India is about population of 1.21 billion. It is now estimated that by 2030, India will most likely overtake China to become the most populous country on the earth. India was the first country in the world to officially launch a national family planning programme (NFPP) in 1952 to reduce birth rate and to stabilize the population at a level consistent with the requirement of national economy. Protecting the young couple from unwanted fertility and educating them to adopt their desired family through informed choice, are among the prerequisites to achieve a TFR of 2.1. To study the prevalence of contraceptive methods among rural population and to study the reasons for not using family planning methods among eligible couples.Methods: A community based cross-sectional study was done among 600 married women in reproductive age, in the three randomly selected Primary health centre areas, one each from the three revenue divisions of Nellore, dated from June 2011 to May 2012.Results: The contraception prevalence rate was 56.3% among whom 91.4% adopted permanent family planning methods.Conclusions: The contraceptive prevalence rate in the study subjects was 56% which was lower than that reported in NFHS-III (67%). Majority of the women opted for permanent sterilization when compared to spacing methods.