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Chinese Journal of Primary Medicine and Pharmacy ; (12): 546-551, 2023.
Artigo em Chinês | WPRIM | ID: wpr-991783

RESUMO

Objective:To analyze the influential factors of hypoalbuminemia in patients with preeclampsia and observe the pregnancy outcomes.Methods:The clinical data of 237 pregnant women with preeclampsia who received treatment in The Sixth Affiliated Hospital of Guangzhou Medical University (Qingyuan People's Hospital) from July 2018 to December 2020 were retrospectively collected and analyzed. These patients were divided into hypoproteinemia (observation group) and no hypoproteinemia (control group) groups according to whether they had hypoproteinemia. The general situation, clinical data, and adverse maternal and infant outcomes were statistically analyzed. Risk factors of hypoalbuminemia were analyzed using a logistic regression model. The predictive efficacy was evaluated using the receiver operating characteristic curve.Results:There were no significant differences in general data between the two groups (all P > 0.05). Multivariate analysis showed that D-dimer ( OR = 1.25, P = 0.004), 24-hour urinary protein ( OR = 1.29, P < 0.001), and total bile acid ( OR = 1.08, P = 0.010) were the independent risk factors for hypoproteinemia in preeclampsia. The predictive efficacy of these three indicators (area under the receiver operating characteristic curve = 0.855, P < 0.001) was greater than that of a single indicator. The incidences of adverse maternal and infant outcomes including placental abruption (9.4%, P = 0.019), liver and kidney dysfunction (34.4%, P < 0.001), pleural and ascitic fluid (28.1%, P = 0.001), fetal intrauterine growth restriction (50.0%, P = 0.001), fundus lesions (6.2%, P = 0.018), HELLP syndrome (9.4%, P = 0.019), mild neonatal asphyxia (15.6%, P = 0.022), severe asphyxia (6.2%, P = 0.049), metabolic acidosis (12.5%, P = 0.001), intrauterine infection (12.5%, P = 0.004), and neonatal hospitalization for more than 20 days (37.5%, P < 0.001) were greater in the observation group compared with the control group. There were no significant differences in postpartum hemorrhage, eclampsia, respiratory distress syndrome, fetal loss, and neonatal death between the two groups (all P > 0.05). Conclusion:D-dimer, 24-hour urinary protein, and total bile acid are independent risk factors for hypoproteinemia in preeclampsia. Patients with preeclampsia complicated by hypoproteinemia have a high risk of adverse maternal and infant outcomes.

2.
Chinese Journal of Practical Nursing ; (36): 12-16, 2013.
Artigo em Chinês | WPRIM | ID: wpr-434411

RESUMO

Objective To explore the present situation of self-care ability among elderly hypertensive patients in the community and its influential factors.Methods 310 elderly hypertensive patients in Hengyang community were studied with a demographic questionnaire,ESCA and SSRS.Results The total mean scores of self-care ability were (105.43±19.25).68.71% of the elderly hypertensive patients were at medium level and 29.35% of them were at high level.Statistically significant relations were found between self-care ability and the following condition factors:education level,marital status,monthly income,obtaining health education status,social support,subjective support,availability,objective support and the severity of hypertension.There were no significant relations with sex and occupations.The results of multiple regression showed that the main factors ranged from high to low including the severity of hypertension,education level,monthly income,subjective support,obtaining health education status and marital status.Conclusions Community health nurses should aim directly at the influential factors,take effective measures and improve their self-care ability.

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