Mammographic findings in different breast cancer subtypes [luminal, Her2 positive, triple negative]

Background: prognosis and management of breast cancer are defined by different variables including histological type, grading, clinical stage, Her2+, estrogen and progesterone receptor conditions. Generally, mammography is one of the most important imaging which is done in breast cancer patients. The aim of this research was to evaluate different mammographic patterns in different breast cancer sub types

Materials and Methods: demographic and clinicopathologic data of 128 breast cancer patients which referred to two academic hospitals were obtained from their registered files and their mammographies were reviewed by two radiologists separately. Patients were categorized into 3 groups of Luminal, triple negative and Her2+ and the checklists were filled out by research team. The mentioned data was then analyzed by the SPSS software version 16

Results: in this study we found significant difference in margins' clarity and axillary lymphadenopathy between mammographic presentations of different breast cancer subtypes [P=0.041] and [P=0.14], respectively; but the difference of other mamographic presentations including mass existence, mass size, margin type, peleomorphic calcification, micro calcification, nipple retraction, skin thickening and tissue distortion were not significantly different between three groups [P>0.05]

Conclusion: results of current study showed no significant difference between mammographic features of different invasive breast cancer subtypes except for axillary lymphadenopathy and ill-defined margins. Since the majority of patients were in premenopausal status, perhaps we can say lower sensitivity of mammography in premenopausal women could not accurately distinguish mammographic differences between invasive breast cancer subtypes in this study

[Report of the frequency of normal renal vascular variants in 62 patients by use of abdominal CT angiography]

In most individuals, each kidney is supplied by a single renal artery and a vein, however multiple renal arteries and veins is not uncommon. In comparison to conventional angiography computed tomographic [CT] angiography is a new and less aggressive measure used for detection of normal renal vascular anatomy and diagnosis of vascular variants. To evaluate the frequency of normal vascular variants in 62 patients [124 Kidneys], underwent abdominal CT Angiography [Aortography]. During a period of one year, abdominal CT angiography was performed in 62 patients, 48 male and 14 female between 7-74 years of age [Mean 25.68 years]. The angiographic images were studied after being reconstituted by use of a computer. There was no complication and all patients tolerated the procedure without any reaction and/or discomfort. One forth of the patients felt some warmness during contrast injection. In 98 [79%] kidneys only one renal artery, in 20 kidneys [16.1%] two arteries, in 4 kidneys three arteries, and in two kidneys four arteries were detected. In 109 kidneys [88%] only one vein and in 15 kidneys [12%] two renal veins were detected and circum-aortic renal vein or renal collar was found only in one case. In this study the frequency of multiple renal vascular variants was less common than those of other studies. By use of spiral CT angiography and reconstitution of images by a computer, renal arteries and veins can be investigated in a short time avoiding invasive sequela or any complication for the patients

Sonographic features of hydatid cysts of the liver [Imam Reza hospital Mashhad 1991 - 1999]

Introduction: More than 50 percent of hydatid cysts of man are seen in the liver and ultrasonography is considered to be one of the primary diagnostic examinations in the evaluation of hydatid cysts, especially when the disease affects the liver or other abdominal viscera. In order to study the sonographic feature of hepatic hydatid cyst a study was undertaken over a period of 8 years on eighty patients and the sensitivity of sonography in the diagnosis of hydatid cysts was 83%. The females were predominant 66.11%, and the average age was 40.22 +/- 10.25 years

Six different types of sonographic images of hydatid cysts were characterized in the study: multiloculated cysts, Calcified cysts, Cysts with collapsed membranes, unilocular cysts, pseudotumoral types and cysts with absorption of sound. The three first types of sonographic images of the cyst can suggest the correct diagnosis, but the other types usually produce diagnostic problems

In our study hepatic hydatid cysts were unilocular in 46.2% of the cases, with predominance in the right lobe [65%]. The complication rate was of 14.80%, with predominance of the supuration [10.12%]