hydro electrolytic disorders in the primary hypothyroidism

This study reports the hydroelectrolytic disorders observed in 14 cases of primary hypothyroidism. Their exploration involves a water-loading test, an hydromineral and hormonal evaluation, the latter includes thyroid and adrenocortical functions, neurophysin ll and ADH levels. This explorations allows the authors to discuss some pathogenic mechanisms: hypervasopresinism, renal, thyroid and adrenal insufficiency. The results show, at patients affected with hypothyroidism, a plasma hypoosmolality, an hyponatremia, and urinary hyperosomlality and an impaired water excretion. Our findigns are in agreement with those observed in the medical litterature. The renal factors seem in part involved in the genesis of these perturbations