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1.
Artigo | IMSEAR | ID: sea-202997

RESUMO

Introduction: Hyperventilation syndrome refers to acollection of physical and emotional symptoms, broughtabout by hyperventilation. Though it is a relatively commonpresentation to the emergency department, there are only a fewstudies on hyperventilation syndrome (HVS) especially fromIndia. This study aims at studying the factors associated withhyperventilation syndrome in the current study population.Material and methods: A cross sectional study wasconducted on 83 patients with HVS. Patient responses wererecorded on Nijmegen questionnaire and Perceived stressscale and analyzed with descriptive statistics.Results: Study population included 83 patients, 78.32% ofthe populations were females and 21.68% were males. Themean age of the population is 19.28 years. 66.26% wereadolescents, 81.92% are students and 68.67% were residingin hostel. 12.05% had previous episodes of hyperventilation.Carpo-pedal spasm was the presenting symptom in 40.96%population and exams were the cause of stress for 32.5%population. The mean score on perceived stress scale is 24.92.59.03% had moderate and 38.55% had severe stress as perscores on perceived stress scale.Conclusion: High student population presenting with HVSand exams being the precipitating stressor, high scores onperceived stress scale emphasizes the need to address the needfor stress free curriculum and greater insights in to the issue.

2.
Artigo | IMSEAR | ID: sea-202995

RESUMO

Introduction: The number of smartphone users in India isshowing a rapidly increasing trend in the last few years. Theexpected user base is nearly one in three by 2021 in India.The evidence on compulsive smartphone use is growingmaking it an addiction along with raising concerns on othermental health issues. The current study aimed to find out theextent of problematic smart phone usage and various variablesassociated with smart phone addiction in the study population.Material and methods: A cross-sectional study wasconducted on 186 participants. Responses were recordedonline through a questionnaire on SAS-SV and analyzed bydescriptive statistics.Results: Study showed 24.2% (45 participants) of studypopulation have smart phone addiction. Male gender, earlyexposure to smart phone, low income, and residence in a citypredicted problematic smart phone usage.Conclusion: People across ages, residence, occupation, andsocial strata are involved with smart phone with one in fourbeing problematic smart phone users.

3.
Pakistan Journal of Pharmaceutical Sciences. 2010; 23 (3): 259-265
em Inglês | IMEMR | ID: emr-98168

RESUMO

To investigate the colon specificity of novel natural polymer khaya gum and compare with guar gum. Release profile of tablets was carried out in presence and absence of rat cecal contents. The fast disintegrating core tablets of budesonide, were initially prepared by direct compression technique. Later, these tablets were coated with khaya gum or guar gum. After suitable pre compression and post compression evaluation, these tablets were further coated using Eudragit L-100 by dip coating technique. X-ray images were taken to investigate the movement, location and the integrity of the tablets in different parts of gastro intestinal tract in rabbits. The release profiles revealed that khaya gum or guar gum, when used as compression coating, protected the drug from being released in the upper parts of the gastro intestinal tract to some extent but the enteric coated formulations completely protected the drug from being released in the upper parts of the gastro intestinal tract, and released the drug in the colon by bacterial degradation of gums. It was found that both the polysaccharide polymers exhibited different release profiles in presence and absence of rat cecal contents. However, further enteric coat helped in targeting the drug to colon very effectively. Better dissolution models revealed the colon specificity of polysaccharides and alone can not be used either for targeting the drug to the colon or for sustaining or controlling the release of drug


Assuntos
Animais , Masculino , Polímeros/administração & dosagem , Colo/metabolismo , Meliaceae , Budesonida/administração & dosagem , Galactanos/administração & dosagem , Coelhos , Ratos , Comprimidos , Portadores de Fármacos
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