Relationship between Perceived Stigma for Psychological Helps and Depression in North Korean Defectors / 신경정신의학

OBJECTIVES: This study was implemented for North Korean defectors to understand the relationship between perceived stigma for psychological helps and depression. METHODS: Two hundred defectors from North Korea were subjects in this study, including 28 males and 172 females. Both self-questionnaires and interviews were conducted. Patient Health Questionnaires-9 (PHQ-9) was used to measure depression scores. Stigma Scale for Receiving Psychological Help (SSRPH) for stigma and Multidimensional Scale of Perceived Social Support (MSPSS) were used to determine social supportive levels that they recognize. RESULTS: In the initial analysis, SSRPH was associated with PHQ-9. Multiple regression analysis to identify the relationship of stigma for subjects' psychological helps on depression showed that staying longer than five years in the third country, working, high MSPSS score, and low SSRPH were negatively associated with the PHQ-9. CONCLUSION: The stigma among North Korean defectors for psychological help is positively associated with depression. Perceived stigma may act as a barrier to the initiation and maintenance of psychiatric treatment who subjects in need of psychological help. Understanding the relationship between perceived stigma for psychological help and depression is important.

Effect of cholestyramine on the formation of pigment gallstone in high carbohydrate diet-fed hamsters

This study was designed to investigate the effect of cholestyramine on the formation of pigment gallstones in high carbohydrate diet-fed hamsters and whether that effect occurred because of cholecystokinin action. Forty seven hamsters were divided into three groups: group I(n = 16) was fed on normal rodent chow(43% carbohydrate), group II(n = 14) was fed on a high CHO diet(65% carbohydrate), group III(n = 17) was fed on a high CHO diet containing 4% cholestyramine. Gallstones developed in 0% of group I, 42.9% of group II and 5.9% of group III(P 0.05). In gallbladder bile analysis, there was also no significant difference between group II and group III in cholesterol, phospholipid, total calcium, total bilirubin and bile acid levels. In conclusion, cholestyramine decreases the frequency of pigment gallstone formation in high CHO diet-fed hamsters, but it is not clear whether the mechanism of cholestyramine decreasing the gallstone formation is due to the action of cholecystokinin.