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Objective:To analyze parents' knowledge, attitudes and practice (KAP) on antibiotics use in children.Methods:A survey of parents' KAP on antibiotics use in children was conducted among 482 parents in Tangqiao community who were visiting the vaccination unit of our center during January to June 2018. The influencing factors of patients' KAP on antibiotics use in children were investigated with univariater and multivariate logistic regression analysis.Results:In terms of knowledge, 89.0% (429/482) of parents agreed that common cold did not require antibiotics treatment; 88.8% (428/482) of parents knew that antibiotics had adverse reactions; 82.0% (395/482) of parents knew that overuse of antibiotics would increase the possibility of drug resistance of pathogenic bacteria; and 69.7% (327/482) of the relevant knowledge acquisition came from doctors. In terms of attitudes, 84.1% (405/482) of the parents agreed with the phenomenon of excessive use of antibiotics in our country; 68.2% (405/482) of the parents agreed that they should follow the doctor's instruction but not ask the doctor to prescribe drugs; 30.7% (148/482) parents thought they had enough knowledge about antibiotics drugs; 24.7% (148/482) parents were willing to use more expensive antibiotics for their children. In terms of practice, 13.9% (67/482) of parents would buy antibiotics by themselves; 35.7% (172/482) of parents had antibiotics at home. Multi-factor regression analysis results showed that parents with high annual family income are likely to better understand antibiotics ( OR=2.619, 95 %CI: 1.431—4.793); parents who had antibiotics at home ( OR=4.713, 95 %CI: 1.964—11.309)and purchased antibiotics by themselves ( OR=2.768, 95 %CI: 1.237—6.194) were more likely to use antibiotics for their children. Conclusion:There are still some problems in parents' knowledge, attitude and behavior of using antibiotics in children in the community, and public education on rational use of antibiotics in children is necessary.
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OBJECTIVE To type Staphylococcus epidermidis and analyze its polymorphism by randomly amplified polymorphic DNA(RAPD),and provide the method for analysis of homogeneity of S.epidermidis.METHODS Twenty one collected strains from ophthalmology ward were analyzed using random primer RAPD1 with RAPD.RESULTS On the basis of bands,difference of clinical strains was analyzed.Twenty one strians of S.epidermidis were divided into 5 patterns.Among them type Ⅰ taken 71 percent(15/21).CONCLUSIONS Typing of S.epidermidis by RAPD at molecular level is very rapid,easy and reliable.It can apply to track pathogens of the hospital and study epidemiology of the bacteria.