Growth of children with thalassemia.

Background: Present observational study, to surveying the growth of children with thalassemia from Solapur District, Maharashtra State, India. Aims: The purpose of this article is to determine the growth of thalassemia in children by analyzing age and gender. One hundred twenty five thalassemic children’s with age 6 months to 18 Years, coming for to get blood transfusion from different parts of Solapur district during June 1st , 2009 to May 1st, 2013. The questionnaires included general information, medical and dental history. Results: This clinical research studied 125 patients, 73 males and 52 females. The growth of thalassemic children was observed and compared with Indian Standard Height Chart. Normal growth was: male (13.61%), female (19.23%) avarage (16.00%); growth retardation was: male (86.30%), female (80%) averages (84.00%) were observed. Conclusions: Thalassemia major is a serious medical problem. Growth retardation is commonly seen in poly-transfused beta thalassemia patients.

Mortality In Thalassemic Patients From Solapur District, Maharashtra State, India.

Objective: The aim of the present study is to surveying the mortality in thalassemic patients from Solapur District, Maharashtra State, India. Methods: Present observational survey study, one hundred twenty five clinically proved by their medical reports, cases of thalassemic children's with age 6 months to 18 Years, coming for to get blood transfusion from different parts of Solapur district. Results: The results indicates that the increased mortality during 11-15 years of age. As a result, transfusional iron overload can cause increased morbidity and premature mortality in thalassemia patients. This study will be helpful in further defining the morbidity and mortality in thalassemic patients.

Prevalence of hepatitis-B surface antigen (HBsAg) positivity in Solapur District, Maharashtra State, India.

Background: Hepatitis B virus is a partially double-stranded circular DNA virus and is a member of the Hepadnaviridae family. The virus consists of a core capsid which contains viral DNA and this is surrounded by an envelope containing surface antigen (HBsAg). Both whole, incomplete virus particles, consisting entirely of HBsAg, are produced during replication of HBV. The HBsAg particles vary greatly in morphology and are found in high concentrations in early acute infection and continue to be produced in chronic disease.1 Objectives: Diagnostic potential of Hepatitis-B surface antigen (HBsAg) positivity and its prevalence was evaluated among volunteers from various localities in Solapur District, Maharashtra State, India. Methodology: The prevalence of hepatitis B surface antigen (HBsAg) was studied from Solapur, Maharashtra State, India, among 767 volunteers (male 470 and female 297), aged 05-55 years volunteers, who required medical check-ups. Blood samples, collected during March to May 2010, were tested for HBsAg using a third-generation ELISA kit. Results: Of the 767 volunteers, male 1.82% and female 1.17% were positive for HBsAg. The results revealed that hepatitis B infection in the target group was below the intermediate endemicity. Conclusion: This study demonstrates that proper training of new entrants in the medical field can be pivotal in preventing HBsAg and it is advocated that a programme for education, vaccination and prophylaxis must be implemented in all healthcare set ups.