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Three key ethical issues in neurotherapeutics research are discussed: the ethical challenges arising from changes in the financial incentive of researchers and their institutions,risk-benefit analysis on testing innovative interventions,and the research for informed consent.
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The clinical application of xenotransplantation can provide unlimited donator organs,and promote the rapid development of organ transplantation.Xenotransplantation must overcome rejection and cross-species infection,and the latter adverse reaction is known as the biggest potential danger brought by xenotransplantation.Although cross-species infection caused by xenotransplantation has not yet occurred,test-tube experiments have already confirmed the possibility of cross-species infection.Besides,ethical issues related to the use of animal organs have been a heated social concern.
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The hospital have to arrange discussions about carrying out or giving up life-support treatment such as gastrostomy artificial feeding on critical ill patients with patients themselves or their family members.In this article,we expatiate on the present ethical situation,problems,value assessment,recommendations on this treatment.
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The shortage of human hearts has brought the current research focus on finding an animal source as substitute hearts.The immunological barriers to cardiac xenotransplantation are now more clearly defined,allowing retrospective interpretation of past clinical experience in humans.Due to physiological compatibilities as well as ethical and infectious considerations,pigs have now emerged as the most likely source of future xenografts.With the introduction of transgenic pigs expressing human complement regulatory proteins and new immunosuppressive strategies have shown early promise in the laboratory,cardiac xenotransplantation has been the social focus.This article explores ethical issues that surround developments in this field.