Avaliação da qualidade de vida, capacidade funcional e força da musculatura respiratória em pacientes com insuficiência cardíaca / Evaluation of quality of life, functional capacity and strength of respiratory and muscles in patients with heart failure

A insuficiência cardíaca (IC) é uma síndrome clínica, via final comum de diversas doenças cardíacas. O estudo teve como objetivo avaliar a qualidade de vida, a capacidade funcional e a força muscular respiratória em pacientes com IC classe funcional I e II. Tratou-se de um estudo observacional transversal, com amostra composta por 20 indivíduos com faixa etária entre 58 e 82 anos, em acompanhamento clínico no Centro Clínico de Especialidades Médicas de Patos de Minas. Após a realização dos testes, foi observado em relação à qualidade de vida que o domínio mais comprometido foi o de limitação por aspectos físicos. Não houve limitação na capacidade funcional e na força muscular respiratória, devido aos indivíduos realizarem acompanhamento fisioterapêutico. A IC gera um impacto negativo sobre a qualidade de vida e que a fisioterapia é indispensável no acompanhamento e prognóstico desta população. (AU)

Heart failure (HF) is a clinical syndrome, the common end-stage of several heart diseases. The study aimed to evaluate the quality of life, functional capacity and respiratory muscle strength in patients with HF functional class I and II. This was a cross-sectional study, with a sample of 20 individuals aged between 58 and 82 years, under clinical follow-up at the Clinical Center of Medical Specialties of Patos de Minas. After performing the tests, it was observed in relation to the quality of life that the most compromised domain was that of limitation by physical aspects. There was no limitation in the functional capacity and in the respiratory muscle strength, due to the individuals performing physiotherapeutic follow-up. It is concluded that HF has a negative impact on the quality of life and that physical therapy is essential in the monitoring and prognosis of this population. (AU)

Birth weight and risk of childhood solid tumors in Brazil: a record linkage between population-based data sets / El peso al nacer y el riesgo de formación de tumores sólidos en la niñez en el Brasil: vinculación de registros entre conjuntos de datos poblacionales

ABSTRACT Objective To analyze the relationship between the development of childhood solid tumors and 1) birth weight and 2) fetal growth, using two Brazilian population-based data sets. Methods A case–cohort study was performed using two population-based data sets, and linkage between the Live Birth Information System (Sistema de Informação sobre Nascidos Vivos, SINASC) and 14 population-based cancer registries (PBCRs) was established. Four controls per case were chosen randomly from the SINASC data set. Tumors were classified as central nervous system (CNS), non-CNS embryonal, and other tumors (“miscellaneous”). Adjustments were made for potential confounders (maternal age, mode of delivery, maternal education, birth order, gestational age, sex, and geographic region). Odds ratios (ORs) with 95% confidence intervals (CIs) were computed using unconditional logistic regression analysis. Results In a trend analysis, for every 500 g of additional birth weight, the crude OR was 1.12 (CI: 1.00–1.24) and the adjusted OR was 1.02 (CI: 0.90–1.16) for all tumors. For every 1 000 g of additional birth weight, the crude OR was 1.25 (CI: 1.00–1.55) and the adjusted OR was 1.04 (CI: 0.82–1.34) for all tumors. Among children diagnosed after reaching the age of 3 years, in the miscellaneous tumor category, the OR was significantly increased for every additional 500 g and 1 000 g of birth weight. Conclusions The study data suggested that increased birth weight was associated with childhood solid tumor development, especially among children more than 3 years old with “miscellaneous” tumors.

RESUMEN Objetivo Analizar la relación entre la aparición de tumores sólidos en la niñez y 1) el peso al nacer y 2) el crecimiento fetal, a partir de dos conjuntos de datos poblacionales del Brasil. Métodos Se efectuó un estudio de casos en una cohorte a partir de dos conjuntos de datos poblacionales y se vinculó el sistema de información de nacidos vivos (Sistema de Informação sobre Nascidos Vivos, SINASC) con 14 registros oncológicos poblacionales. Se eligieron al azar cuatro controles por caso del conjunto de datos del SINASC. Los tumores se clasificaron en tres tipos: del sistema nervioso central (SNC), embrionarios ajenos al SNC y otros (“misceláneos”). Se hicieron ajustes en función de los posibles factores de confusión (edad materna, modalidad de parto, educación materna, orden de nacimiento, edad gestacional, sexo y región geográfica) y se calcularon las razones de posibilidad (OR) con un intervalo de confianza (IC) del 95 % mediante análisis de la regresión logística incondicional. Resultados En el análisis de las tendencias, se observó que, en todos los tumores, cada 500 g adicionales de peso al nacer la OR bruta fue de 1,12 (IC: 1,00-1,24) y la OR ajustada, de 1,02 (IC: 0,90-1,16), mientras que, cada 1 000 g adicionales, la OR bruta fue de 1,25 (IC: 1,00-1,55) y la OR ajustada, de 1,04 (IC: 0,82-1,34). En cuanto a los niños diagnosticados después de los 3 años de edad, en la categoría de tumores misceláneos, la OR fue significativamente más alta con cada 500 g y 1 000 g adicionales de peso al nacer. Conclusiones Los datos del estudio indican que el peso alto al nacer está asociado a la aparición de tumores sólidos en la niñez, especialmente de la categoría “misceláneos” y en los niños mayores de 3 años de edad.