RESUMO
To evaluate the factors that influence the prognosis of patients with Phyllodes tumour. Interventional case series from April 2002 to April 2006. Setting: Department of Surgery, Surgical Ward-2, Jinnah Postgraduate Medical Centre, Karachi. Patients: Twenty two patients of Phyllodes tumour breast that were operated. Detailed data of all the patients was collected. Diagnosis of Phyllodes tumour was made on good clinical examination, ultrasonography, mammography and trucut biopsy. Primary treatment included wide local excision in 19 cases and mastectomy in three cases. All patients were females with a mean age of 31 years. Left breast was affected more [60%] than the right and a painless lump was the commonest presentation. Patients were divided into three groups after final histopathology report. Ten patients were reported as benign phyllodes who showed no recurrence on follow-up and four patient as borderline phyllodes, who developed recurrence within 12-18 months; while eight patients were reported as malignant phyllodes. The key prognostic factors are status of margins, histological type and the size of the tumour. Trucut biopsy has greater yield of diagnosis and surgery remains the mainstay of treatment for Cystosarcoma Phyllodes