RESUMO
[Objective] To study the effect of eletro-acupuncture of Neiguan on the CGRP in rats' plasma and its functional mechanism.[Method] Inject subcutaneously GTN to make rats migraine model.After electro-acupuncturing Neiguan,take radio-immune method to measure the CGRP content in rats' plasma of experimental group.[Result] Electro-acupuncturing Neiguan can reduce rats CGRP content.[Conclusion] To inject subcutaneously GTN can raise rats' plasma CGRP content,electro-acupuncturing Neiguan can reduce risen CGRP,regulate vascular extension,improve nerve inflammation,thus relieve migraine symptoms.
RESUMO
Purpose: In order to explore the clinical mechanism of Neiguan (PC 6) in the treatment of acute seizure of migraine and the relationship between Neiguan (PC 6) and cerebral blood flow. Methods: Clinically, 30 cases of the patients with acute seizure of migraine (ascending phase) were selected, in TCD abnormality, and divided randomly into the treatment group and control group, 15 cases in each group. In acute seizure of migraine, Neiguan (PC 6)was punctured with electric stimulation on the healthy side of the patients in the treatment group and Xuehai (SP 10) was punctured with electric stimulation on the healthy side of the patients in the control group. TCD was determined in the patients 30 min before and after the treatment. Results and conclusion: After transdermal electric stimulation on Neiguan (PC 6),the velocity of intracranial blood flow was obviously slowed down, indicating that transdermal electric stimulation on Neiguan (PC 6) can effectively relieve the spasm of intracranial blood vessels and also shows its relative specificity.