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Braz. j. med. biol. res ; 22(7): 885-7, 1989. ilus
Artigo em Inglês | LILACS | ID: lil-83208

RESUMO

The pressor responses to common carotid occlusion were studied in conscious female rats throughout the estrous cycle, after gonadectomy and after gonadectomy followed by treatment with estrogen and progesterone. The initial peak pressor response was highest during proestrus and fell significantly over the remaining 3 days of the estrous cycle. The maintained pressor response was relatively unchanged throughout the cycle, except during diestrus 1 when it decreased markedly. Gonadectomy reduced and treatment with estradiol alone increased the initial pressor component, respectively. Treatment of gonadectomized rats with estradiol plus progesterone enhanced both components. These findings suggest that gonadal steroid hormones are important modulators of the pressor to common carotid occlusion


Assuntos
Ratos , Animais , Feminino , Arteriopatias Oclusivas/fisiopatologia , Pressão Arterial , Doenças das Artérias Carótidas/fisiopatologia , Estro , Estradiol/uso terapêutico , Ovariectomia , Progesterona/uso terapêutico , Ratos Endogâmicos
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