Infecciones hospitalarias: Gastos sobreañadidos por antibióticos de uso parenteral. Análisis del cuatrenio 2000-2003 / Hospital infections: Overadded expense due to the use of parenteral antibiotics. Analysis of the 4-year-period 2000-2003

Año tras año los costos hospitalarios se elevan considerablemente debido al incremento de las infecciones asociadas a procederes en instituciones de Salud, que son un indicador indiscutible de la calidad de la atención. Se realiza un trabajo descriptivo y retrospectivo, para analizar las Infecciones hospitalarias de nuestro centro, las tasas globales y por servicios, los gérmenes circulantes y los mapas microbianos del trienio. Se analizaron 284 historias clínicas de los pacientes con Infección hospitalaria en busca de la antibióticoterapia utilizada; se calcularon los gastos en antibióticos inyectables en estos casos. Se concluye que en los 3 años, los gérmenes más frecuentes fueron las enterobacterias, los más resistentes frente a los antibióticos fueron los BNF y los estafilococos, el antibiótico que presentó mayor resistencia fue la penicilina, los consumos mayoritarios de antibióticos inyectables los tuvieron el servicio de ginecología en el año 2000, mientras que en el año 2001,el 2002 y el 2003 fue el Servicio de Obstetricia; el gasto en antibióticos inyectables, en los casos sépticos fue: año 2000: $13493.09; año 2001: $20547.32; año 2002: $24842.62; año 2003: $14850.05.

Year after year hospital costs increase considerably due to the rise of infections associated with procedures in health institutions. It is an unquestionable indicator of the quality of care. A descriptive and retrospective study was conducted to analyze hospital infections in our center, the global rates and the rates by services, the circulating germs and the microbial maps of the 3-year-period. 284 medical histories from patients with hospital infections were analyzed searching for the used antibiotic therapy. The expenses in injectable antibiotics were calculated in these cases. It was concluded that in 3 years, the most common germs were the Enterobacteria, the BNF and the Staphylococcus. Penicillim was the most resistant antibiotic. The services with the highest consumption of injectable antibiotics were the Gynecology Service in the year 2000, and the Obstetrics Service in 2001, 2002 and 2003. The expense in injectable antibiotics, in the septic cases, was as follows: 2000: $13493.09; 2001: $20547.32; 2002: $24842.62; and 2003: $14850.05.

Non increased neuron-specific enolase concentration in cerebrospinal fluid during first febrile seizures and year follow-up in pediatric patients

Febrile seizures are the commonest acute neurological disorder of early childhood. Studies suggested that febrile seizures are previous acute events from a more serious neurological problem. Due to neuron-specific enolase is generally accepted as a marker for neuropathological processes in the brain, 16 pediatric patients were studied during their first seizures and a year after it. Neuron-specific enolase in cerebrospinal fluid and blood were analysed by an immune enzyme assay. Non pathological neuron-specific enolase values were obtained in both periods in the group of patients. There no significative differences when paired series statistics test was performed with 95 per cent of confidence. Neuron-specific enolase appears not to be a marker for febrile seizures because its concentration not be increased in cerebrospinal fluid in this group of patients.