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1.
Rev. bras. med. esporte ; 29: e2022_0672, 2023. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1423581

RESUMO

ABSTRACT Introduction: With the promotion of rock climbing in the Tokyo Olympic Games in 2020 and the China National Games in 2017, the sport has been spread to the general public, and the country has paid more attention to its development. Objective: Study the effects of rock-climbing exercise on athletes' performance in physical training. Methods: A comparative study was conducted on the physical training of rock climbers through literary consultation, experience, and mathematical statistics aiming to explore the impact of the sport on physical training in rock climbers. Fifteen professional rock-climbing team athletes participated in this research. Results: A significant difference was found in strength quality between the experimental group and the control group (p<0.05), there were very significant differences in the fixed bar, push-ups, and 1min abdominal exercises (p<0.01) after the experiment, there were significant differences in speed, agility, and endurance between the experimental group and the control group (p<0.05), with emphasis on motor coordination and speed quality (p<0.01). Conclusion: Integrating physical training with rock climbing training has a remarkable effect on improving athletes' physical performance. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.


RESUMO Introdução: Com a promoção da escalada em rocha nos Jogos Olímpicos de Tóquio em 2020 e nos Jogos Nacionais da China em 2017, o esporte foi difundido pelo público em geral e o país tem dado mais atenção ao seu desenvolvimento. Objetivo: Estudar os efeitos do exercício de escalada em rocha sobre o desempenho do treinamento físico nos atletas. Métodos: Foi realizado um estudo comparativo sobre o treinamento físico de escaladores em rocha através de consulta literária, experiência e estatísticas matemáticas visando explorar o impacto do esporte no treinamento físico em escaladores. Participaram dessa pesquisa 15 atletas profissionais da equipe de escalada em rocha. Resultados: Foi encontrada uma diferença significativa na qualidade da força entre o grupo experimental e o grupo controle (p<0,05), houve diferenças muito significativas nos exercícios de barra fixa, flexões e abdominais de 1min (p<0,01), após o experimento, houve diferenças significativas na velocidade, agilidade e resistência entre o grupo experimental e o grupo controle (p<0,05), com destaque entre a coordenação motora e a qualidade da velocidade (p<0,01). Conclusão: A integração do treinamento físico com o treinamento de escalada em rocha tem um efeito notável sobre a melhoria do desempenho físico dos atletas. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.


RESUMEN Introducción: Con la promoción de la escalada en roca en los Juegos Olímpicos de Tokio en 2020 y los Juegos Nacionales de China en 2017, este deporte se ha extendido al público en general y el país ha prestado más atención a su desarrollo. Objetivo: Estudiar los efectos del ejercicio de escalada en roca sobre el rendimiento del entrenamiento físico en atletas. Métodos: Se realizó un estudio comparativo sobre la preparación física de los escaladores mediante la consulta literaria, la experiencia y la estadística matemática con el objetivo de explorar el impacto del deporte en la preparación física de los escaladores. Quince atletas profesionales de equipos de escalada en roca participaron en esta investigación. Resultados: Se encontró una diferencia significativa en la calidad de la fuerza entre el grupo experimental y el grupo de control (p<0,05), hubo diferencias muy significativas en los ejercicios de barra fija, flexiones y abdominales de 1min (p<0,01), después del experimento, hubo diferencias significativas en la velocidad, agilidad y resistencia entre el grupo experimental y el grupo de control (p<0,05), con énfasis en la coordinación motora y la calidad de la velocidad (p<0,01). Conclusión: La integración del entrenamiento físico con el de escalada en roca tiene un efecto notable en la mejora del rendimiento físico de los deportistas. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.

2.
China Journal of Orthopaedics and Traumatology ; (12): 448-453, 2022.
Artigo em Chinês | WPRIM | ID: wpr-928339

RESUMO

OBJECTIVE@#To explore the clinical effect of percutaneous endoscopic lumbar discectomy in the treatment of adjacent segment lumbar disc herniation after lumbar fusion.@*METHODS@#From February 2010 to June 2018, 64 patients with adjacent segment lumbar disc herniation after lumbar fusion were retrospectively analyzed and divided into observation group and control group. In observation group, there were 23 males and 10 females performed with percutaneous endoscopic lumbar discectomy, including 27 cases of single segment fusion and 6 cases of double segment fusion, aged from 55 to 83 years old with an average of (65.7±7.4) years old. In control group, there were 22 males and 9 females performed with traditional open fusion revision, including 25 cases of single-segment fusion and 6 cases of double segment fusion, aged from 51 to 78 years old with an average of(64.8±7.8) years old. The operative time, intraoperative blood loss, fluoroscopy times, postoperative ambulation time and length of postoperative hospital stay were recorded. The clinical efficacy was evaluated by visual analogue scale(VAS) and Oswestry Disability Index(ODI). The complications between two groups were observed.@*RESULTS@#All patients were followed up for at least 2 years. The observation group patients were followed up with an average of (2.4±0.5) years. The control group patients were followed up with an average of(2.6±0.7) years. Compared with control group, operation time, intraoperative blood loss, postoperative ambulation time and length of postoperative hospital stay of the observation group were significantly reduced (P<0.05), and the fluoroscopy times of observation group were significantly increased compared with control group(P<0.05). The VAS of low back and lower limb, and ODI at the latest follow-up between two groups were all significantly improved compared to those of pre-operation (P<0.05). The VAS of low back at each point and ODI at 1, 3 months after operation in observation group was significantly reduced compared with control group(P<0.05), however there was no significant difference in VAS for lower limb between two groups (P>0.05). The difference of complications between two groups was statistically significant (P<0.05).@*CONCLUSION@#Compared with traditional open fusion revision surgery, percutaneous endoscopic lumbar discectomy for the treatment of adjacent segment lumbar disc herniation after lumbar fusion has the advantages of reducing operation time and intra-operative blood loss, shortening ambulation time and the length of postoperative hospital stay, and promoting pain and functional improvement, and decrease incidence of complications. However, long-term clinical efficacy needs further study.


Assuntos
Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Perda Sanguínea Cirúrgica , Discotomia , Discotomia Percutânea , Endoscopia , Degeneração do Disco Intervertebral/cirurgia , Deslocamento do Disco Intervertebral/cirurgia , Vértebras Lombares/cirurgia , Estudos Retrospectivos , Resultado do Tratamento
3.
China Journal of Orthopaedics and Traumatology ; (12): 1142-1147, 2020.
Artigo em Chinês | WPRIM | ID: wpr-879369

RESUMO

OBJECTIVE@#To analyze the causes of vascular injury occurred in oblique lateral interbody fusion for treating lumbar degenerative diseases, and put forward preventive measures.@*METHODS@#There were 235 patients analyzed from October 2014 to May 2017 in five hospitals, who were treated with oblique lateral interbody fusion with or without posterior pedicle screw fixation. There were 79 males and 156 females with an average age of (61.9±13.5) years old (ranged from 32 to 83 years). There were 7 cases of vascular injury, including 4 cases of segmental vessel injury, 1 case of left common iliac artery injury, 1 case of left common iliac veininjury and 1 case of ovarian vein injury.@*RESULTS@#The follow up time ranged from 6 to 36 months, averagely (15.6±7.5) months. There was no pedicle screw loosen or fracture. The low back pain VAS decreased from preoperative 6.7±2.3 to 1.4±0.8 at the latest follow-up, which was statistically difference(@*CONCLUSION@#Oblique lateral interbody fusion technique provides a new method for minimally invasive fusion of lumbar internal fixation. However, it has a risk of vascular injury. In order to effectively prevent the occurrence of vascular injury, the operative indications and careful and meticulous operation should be strictly grasped.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Vértebras Lombares/cirurgia , Região Lombossacral , Parafusos Pediculares , Estudos Retrospectivos , Fusão Vertebral/efeitos adversos , Resultado do Tratamento , Lesões do Sistema Vascular/cirurgia
4.
J Genet ; 2019 Sep; 98: 1-5
Artigo | IMSEAR | ID: sea-215402

RESUMO

The species of Oryza rufipogon. dw was first discovered at Dongxiang, Jiangxi in 1978. It is recognized as abundant in genetic resources with the characteristics of cold and insect resistance. A total of 100.15 Gb raw data was obtained from seven pair-end libraries by Illumina Hiseq4000 platform. Subsequently, a draft assembly genome of O. rufipogon. dw was generated with a final size of 422.7 Mb with a contig N50 of 15 kb and a scaffold N50 of 296.2 bb. The assembly genome size was higher than the estimated genome size (413 Mb) based on k-mer analysis. The identified repeat sequences accounted for 40.09% of the entire genome, and 32,521 protein-coding genes with an average of 4.59 exons per gene was annotated in five databases. Phylogenetic analysis using 1460 single-copy gene, O. rufipogon. dw was close with O. rufipogon by Bayes method. The wild rice species of O. rufipogon. dw divergence was estimated at ∼0.3 million years ago (Mya) from O. rufipogon, and ∼0.6 Mya from the O. sativa. The draft genome of O. rufipogon. dw provided an essential resource for its origin and evolution study.

5.
Rev. Assoc. Med. Bras. (1992) ; 65(5): 678-681, May 2019. graf
Artigo em Inglês | LILACS | ID: biblio-1012972

RESUMO

SUMMARY OBJECTIVE: We describe the case of a diabetic patient who developed vertebral osteomyelitis and bilateral psoas abscess with gas formation due to klebsiella pneumoniae. METHODS: A 64-year-old woman with a 4-year history of type-2 diabetes mellitus was admitted to the Emergency Department. The subject had a 2-day history of high-grade fever associated with chills and a 5-hour history of consciousness. She received empirical treatment with febrifuge, after which her fever decreased. RESULTS: Her fever recurred after an interval of three hours. A computed tomography scan of the abdomen revealed vertebral osteomyelitis and bilateral psoas muscle abscess with gas formation. Blood culture and purulent fluid described the growth of the Klebsiella pneumoniae. The patient received antibiotic therapy and bilateral drainage therapy after the drainage catheter was placed into the abscess cavity by CT-guidance. Due to the serious damage to the vertebral column and permanent pain, the patient underwent minimally invasive internal spinal fixation and recovered successfully. CONCLUSION: A case of vertebral osteomyelitis and bilateral psoas abscess with gas formation caused by Klebsiella pneumoniae in a diabetic patient. Antibiotic therapy, drainage, and minimally invasive internal spinal fixation were performed, which enabled a good outcome.


RESUMO OBJETIVO: Descrever o caso de uma paciente diabética que desenvolveu osteomielite vertebral e abcesso bilateral do psoas com formação de gás causada por klebsiella pneumoniae. MÉTODOS: Uma mulher de 64 anos de idade, com 4 anos de histórico de diabetes mellitus tipo 2, foi admitida no Serviço de Emergência. A paciente apresentava um quadro de dias de febre alta acompanhada de calafrios e um histórico de 5 horas de consciência. Ela recebeu tratamento empírico com antitérmico, após o qual a febre diminuiu. RESULTADOS: A febre retornou após um intervalo de três horas. Uma tomografia computadorizada do abdome revelou osteomielite vertebral e abcesso bilateral do músculo psoas com formação de gás. A cultura do sangue e o fluido purulento revelaram o crescimento de Klebsiella pneumoniae. A paciente recebeu antibióticos e terapia de drenagem bilateral após o cateter de drenagem ser posicionado na cavidade do abscesso com auxílio de TC. Devido a sérios danos à coluna vertebral e a dor permanente, a paciente foi submetida à fixação vertebral interna minimamente invasiva e recuperou-se com sucesso. CONCLUSÃO: Um caso de osteomielite vertebral e abscesso do psoas bilateral com a formação de gás causada por Klebsiella pneumoniae em uma paciente diabética. Antibioticoterapia, drenagem e fixação vertebral interna minimamente invasiva foram realizadas, o que permitiu um bom resultado.


Assuntos
Humanos , Feminino , Osteomielite/cirurgia , Doenças da Coluna Vertebral/cirurgia , Infecções por Klebsiella/cirurgia , Abscesso do Psoas/cirurgia , Complicações do Diabetes/cirurgia , Klebsiella pneumoniae/patogenicidade , Osteomielite/microbiologia , Doenças da Coluna Vertebral/microbiologia , Infecções por Klebsiella/microbiologia , Tomografia Computadorizada por Raios X/métodos , Drenagem/métodos , Reprodutibilidade dos Testes , Resultado do Tratamento , Abscesso do Psoas/microbiologia , Complicações do Diabetes/microbiologia , Gases/metabolismo , Pessoa de Meia-Idade
6.
An. bras. dermatol ; 94(1): 86-88, Jan.-Feb. 2019. graf
Artigo em Inglês | LILACS | ID: biblio-983745

RESUMO

Abstract: We report a case of amelanotic acral melanoma in a 42-year-old Chinese woman. Ten months previously the patient found a 2-cm asymmetric erythematous macular plaque on her left sole. The lesion was diagnosed as verruca plantaris by every physician the patient consulted. One month ago, an enlarged lymph node was detected in the left groin, which biopsy reported as metastatic melanoma. Dermoscopy suggested verruca plantaris, and positron emission tomography (PET) revealed increased glucose metabolism in the macular plaque. Finally, biopsy of the plaque revealed amelanotic melanoma. Misdiagnosis and diagnostic delay are usually associated with poorer patient outcomes. Awareness of atypical presentations of acral melanoma is thus important for decreasing misdiagnosis rates and improving patient outcomes.


Assuntos
Humanos , Feminino , Adulto , Neoplasias Cutâneas/patologia , Verrugas/patologia , Melanoma Amelanótico/patologia , Dermatoses do Pé/patologia , Neoplasias Cutâneas/diagnóstico , Biópsia , Verrugas/diagnóstico , Melanoma Amelanótico/diagnóstico , Dermoscopia , Diagnóstico Diferencial , Erros de Diagnóstico , Diagnóstico Tardio , Dermatoses do Pé/diagnóstico , Metástase Linfática
7.
Clinics ; 71(10): 562-569, Oct. 2016. tab, graf
Artigo em Inglês | LILACS | ID: lil-796866

RESUMO

OBJECTIVES: Septic pulmonary embolism is an uncommon but life-threatening disorder. However, data on patients with septic pulmonary embolism who require critical care have not been well reported. This study elucidated the clinicoradiological spectrum, causative pathogens and outcomes of septic pulmonary embolism in patients requiring critical care. METHODS: The electronic medical records of 20 patients with septic pulmonary embolism who required intensive care unit admission between January 2005 and December 2013 were reviewed. RESULTS: Multiple organ dysfunction syndrome developed in 85% of the patients, and acute respiratory failure was the most common organ failure (75%). The most common computed tomographic findings included a feeding vessel sign (90%), peripheral nodules without cavities (80%) or with cavities (65%), and peripheral wedge-shaped opacities (75%). The most common primary source of infection was liver abscess (40%), followed by pneumonia (25%). The two most frequent causative pathogens were Klebsiella pneumoniae (50%) and Staphylococcus aureus (35%). Compared with survivors, nonsurvivors had significantly higher serum creatinine, arterial partial pressure of carbon dioxide, and Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores, and they were significantly more likely to have acute kidney injury, disseminated intravascular coagulation and lung abscesses. The in-hospital mortality rate was 30%. Pneumonia was the most common cause of death, followed by liver abscess. CONCLUSIONS: Patients with septic pulmonary embolism who require critical care, especially those with pneumonia and liver abscess, are associated with high mortality. Early diagnosis, appropriate antibiotic therapy, surgical intervention and respiratory support are essential.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Bacteriemia/diagnóstico por imagem , Bacteriemia/terapia , Cuidados Críticos/métodos , Embolia Pulmonar/diagnóstico por imagem , Embolia Pulmonar/terapia , Bacteriemia/microbiologia , Bacteriemia/mortalidade , Bactérias/isolamento & purificação , Mortalidade Hospitalar , Unidades de Terapia Intensiva , Abscesso Hepático/diagnóstico por imagem , Abscesso Hepático/microbiologia , Abscesso Hepático/mortalidade , Abscesso Hepático/terapia , Pulmão/diagnóstico por imagem , Pulmão/patologia , Prontuários Médicos , Tomografia Computadorizada Multidetectores/métodos , Insuficiência de Múltiplos Órgãos/microbiologia , Insuficiência de Múltiplos Órgãos/mortalidade , Pneumonia/diagnóstico por imagem , Pneumonia/microbiologia , Pneumonia/mortalidade , Pneumonia/terapia , Embolia Pulmonar/microbiologia , Embolia Pulmonar/mortalidade , Estudos Retrospectivos , Estatísticas não Paramétricas
8.
Asian Pacific Journal of Tropical Medicine ; (12): 193-196, 2016.
Artigo em Chinês | WPRIM | ID: wpr-951473

RESUMO

Objective: To investigate the influence of lactulose on immunity of hepatocellular carcinoma (HCC) patients with hepatocirrhosis and hypersplenism after double-interventional therapies. Methods: A total of 40 HCC patients with hepatocirrhosis and hypersplenism, hospitalized during January 2013 to June 2014, were enrolled and randomized into control group and observation group. Both groups received partial splenic embolization combined with transcatheter arterial chemoembolization. Besides, observation group orally took lactulose 30 mL/d. Four days before interventional therapies and at days 1, 3, 7 and 14 after therapies, fasting venous blood was collected to detect white blood cell count, red blood cell count (RBC), and platelet count (PLT). Four days before therapies and at days 7 and 14 after therapies, the levels of alanine aminotransferase, aspartate transaminase, total bilirubin, malondialdehyde, super-oxide dismutase (SOD), IFN-γ, and IL-4 as well as the distribution of T cell subsets in peripheral blood were tested. Complications were observed after interventional therapies. Results: Before interventional therapies the levels of white blood cell count, PLT and RBC in both groups showed no difference, while after interventional therapies the levels of PLT and RBC in both groups showed an increasing tendency (P < 0.05). At day 14 after interventional therapies, the level of blood cell as well as that of SOD, IFN-γ and IL-4 in serum were significantly higher than that before therapies; meanwhile, the levels of alanine aminotransferase and total bilirubin of observation group after therapies were significantly lower than before and control group (P < 0.05), the levels of CD4

9.
Asian Pacific Journal of Tropical Medicine ; (12): 193-196, 2016.
Artigo em Inglês | WPRIM | ID: wpr-820290

RESUMO

OBJECTIVE@#To investigate the influence of lactulose on immunity of hepatocellular carcinoma (HCC) patients with hepatocirrhosis and hypersplenism after double-interventional therapies.@*METHODS@#A total of 40 HCC patients with hepatocirrhosis and hypersplenism, hospitalized during January 2013 to June 2014, were enrolled and randomized into control group and observation group. Both groups received partial splenic embolization combined with transcatheter arterial chemoembolization. Besides, observation group orally took lactulose 30 mL/d. Four days before interventional therapies and at days 1, 3, 7 and 14 after therapies, fasting venous blood was collected to detect white blood cell count, red blood cell count (RBC), and platelet count (PLT). Four days before therapies and at days 7 and 14 after therapies, the levels of alanine aminotransferase, aspartate transaminase, total bilirubin, malondialdehyde, super-oxide dismutase (SOD), IFN-γ, and IL-4 as well as the distribution of T cell subsets in peripheral blood were tested. Complications were observed after interventional therapies.@*RESULTS@#Before interventional therapies the levels of white blood cell count, PLT and RBC in both groups showed no difference, while after interventional therapies the levels of PLT and RBC in both groups showed an increasing tendency (P < 0.05). At day 14 after interventional therapies, the level of blood cell as well as that of SOD, IFN-γ and IL-4 in serum were significantly higher than that before therapies; meanwhile, the levels of alanine aminotransferase and total bilirubin of observation group after therapies were significantly lower than before and control group (P < 0.05), the levels of CD4(+)/CD8(+), SOD and IFN-γ were all higher than before and control group (P < 0.05).@*CONCLUSIONS@#Oral administration of lactulose could adjust the imbalance of oxidation system/antioxidant system in HCC patients with hepatocirrhosis and hypersplenism after interventional therapies, and improve the antitumor immunity and prognosis.

10.
Artigo em Inglês | IMSEAR | ID: sea-170337

RESUMO

Background & objectives: Vitamin D insufficiency is prevalent in postmenopausal women and has been related to low bone mineral density (BMD). However, controversial results have been reported for the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and BMD. This study was done to investigate whether serum 25(OH)D levels were associated with BMD in postmenopausal women living in Guangzhou in southern China. Methods: This cross-sectional study involved 119 asymptomatic postmenopausal women, aged 48-85 yr, who were consecutively selected from Guangzhou city. BMD was measured at the lumbar spine and femoral neck. The correlation between serum 25(OH)D levels and BMD wes investigated. Results: With increasing serum 25(OH)D levels categorized as <20, 20-30, and ≥30ng/ml, the PTH levels decreased gradually (P=0.031). Bivariate correlation analyses showed an inverse relationship between serum 25(OH)D and PTH levels after controlling for age and BMI (r=-0.209, P=0.023). Although subjects with vitamin D<30 ng/ml had significantly lower BMD, age- and BMI-adjusted serum 25(OH)D was weakly correlated with BMD at femoral neck (r=0.185, P=0.045), and not at lumbar spine (r=0.172, P=0.063). In multiple regression analyses, serum 25(OH)D was a predictor for BMD at femoral neck (R 2=0.424). However, serum β-CTX was a determinant for BMD at lumbar spine (R 2=0.361). Interpretation & conclusions: Serum 25(OH)D levels showed a positive correlation with BMD at femoral neck and serum β-CTX levels were inversely correlated with BMD at lumbar spine in postmenopausal women. Further studies are needed to elucidate the clinical impact of these findings.

11.
Clinics ; 70(6): 400-407, 06/2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-749791

RESUMO

OBJECTIVES: Septic pulmonary embolism caused by a Klebsiella (K.) pneumoniae liver abscess is rare but can cause considerable morbidity and mortality. However, clinical information regarding this condition is limited. This study was conducted to elucidate the full disease spectrum to improve its diagnosis and treatment. METHOD: We reviewed the clinical characteristics, imaging findings, and clinical courses of 14 patients diagnosed with septic pulmonary embolism caused by a K. pneumoniae liver abscess over a period of 9 years. RESULTS: The two most prevalent symptoms were fever and shortness of breath. Computed tomography findings included a feeding vessel sign (79%), nodules with or without cavities (79%), pleural effusions (71%), peripheral wedge-shaped opacities (64%), patchy ground-glass opacities (50%), air bronchograms within a nodule (36%), consolidations (21%), halo signs (14%), and lung abscesses (14%). Nine (64%) of the patients developed severe complications and required intensive care. According to follow-up chest radiography, the infiltrates and consolidations were resolved within two weeks, and the nodular opacities were resolved within one month. Two (14%) patients died of septic shock; one patient had metastatic meningitis, and the other had metastatic pericarditis. CONCLUSION: The clinical presentations ranged from insidious illness with fever and respiratory symptoms to respiratory failure and septic shock. A broad spectrum of imaging findings, ranging from nodules to multiple consolidations, was detected. Septic pulmonary embolism caused by a K. pneumoniae liver abscess combined with the metastatic infection of other vital organs confers a poor prognosis. .


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Klebsiella pneumoniae , Infecções por Klebsiella/complicações , Abscesso Hepático/complicações , Embolia Pulmonar/microbiologia , Choque Séptico/complicações , Complicações do Diabetes/complicações , Dispneia/etiologia , Febre/etiologia , Infecções por Klebsiella/diagnóstico , Infecções por Klebsiella/microbiologia , Abscesso Hepático/microbiologia , Nódulos Pulmonares Múltiplos/diagnóstico , Derrame Pleural/diagnóstico , Embolia Pulmonar/complicações , Embolia Pulmonar/diagnóstico , Estudos Retrospectivos , Choque Séptico/diagnóstico , Choque Séptico/microbiologia , Tomografia Computadorizada por Raios X/métodos
12.
China Journal of Orthopaedics and Traumatology ; (12): 252-256, 2013.
Artigo em Chinês | WPRIM | ID: wpr-344746

RESUMO

<p><b>OBJECTIVE</b>To evaluate the value of the Centerpiece plate in the cervical single open-door laminoplasty and compared its advantages with conventional suture fixation methods.</p><p><b>METHODS</b>From December 2009 to August 2011,32 patients with cervical spondylotic myelopathy were treated with operation. Of them, 15 cases underwent cervical single open-door laminoplasty and Centerpiece plate fixation (group A),there were 8 males and 7 females,aged from 51 to 65 years old with an average of 60.5 years and ranged in course of disease from 2 to 15 months; 17 cases underwent cervical single open-door laminoplasty and silk suture fixation (group B), there were 9 males and 8 females, aged from 49 to 66 years old with an average of 61.5 years and ranged in course of disease from 1 to 14 months. All the patients with unsteady gait symptom before operation and cervical MR imaging showed spinal cord compression and denaturation. According to standard of Japanese Orthopaedics Association (JOA) to evaluate the spinal nervers function before operation and at 6 months after operation;according to CT scan to determine the sagittal diameter (AP) of upper vertebral canal and cervical activity (ROM).</p><p><b>RESULTS</b>All the patients were followed up from 8 to 20 months with an average of 13 months. All the incisions healed well and no complications such as internal fixation loosening and breakage,spinal cord injury, reclose-door were found. Postoperative symptoms relieved obviously and MRI and CT showed vertebral canal volume expanded significantly. Operative time and blood loss in group A were respectively (155.0+/-12.3) min, (407.0+/-11.8) ml and in group B were respectively (148.0+/-14.4) min, (398.0+/-15.4) ml. There was no significantly differenc, between two groups (P>0.05). JOA score in group A improved from preoperative 9.1+/-2.6 to postoperative 15.5+/-1.8 and in group B improved from preoperative 9.3 +/- 2.1 to postoperative 13.1 +/- 2.5 (P<0.05). CT sagittal diameter (AP) in group A increased from preoperative (10.7+/-2.4) mm to postoperative (17.6+/-3.2) mm and in group B increased from preoperative (11.6+/-1.7) mm to postoperative (15.9+/-2.0) mm (P<0.05). Cervical activity (ROM) in group A be- fore and after operation were respectively (51.0+/-2.6) degrees, (45.0+/-3.5) degrees and in group B were respectively (52.0+/-1.8) and (42.0+/-2.4). There was no significantly difference before operation between two groups (P>0.05) and there was significantly difference after operation between two groups (P<0.05).</p><p><b>CONCLUSION</b>Treatment of cervical spondylotic myelopathy with posterior single open-door laminoplasty and Centerpiece plate fixation can enlarge spinal canal volume,keep original cervical activity, improve postoperative JOA score. The method has obviously advantages compared with traditional suture fixation methods.</p>


Assuntos
Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Placas Ósseas , Vértebras Cervicais , Cirurgia Geral , Laminectomia , Métodos , Canal Medular , Cirurgia Geral , Espondilose , Cirurgia Geral
13.
China Journal of Orthopaedics and Traumatology ; (12): 946-950, 2012.
Artigo em Chinês | WPRIM | ID: wpr-313785

RESUMO

<p><b>OBJECTIVE</b>To systematically assess the clinical efficacy of bone morphogenetic proteins in the treatment of open tibial fractures.</p><p><b>METHODS</b>Based on the principles and methods of Cochrane systematic reviews, the Cochrane Library, PubMed, EMBASE, Chinese Bio-medicine Database, China Journal Full-text Database, VIP database were searched from their establishment to April 2012 in whatever language. Related journals were handsearched as well. Randomized controlled trials (RCTs) of bone morphogenetic protein for the treatment of open tibial fractures were included. The quality of the included trials according to the Cochrane Handbook for Systematic Reviews of Interventions Version was assessed. The Cochrane Collaboration's software RevMan 5.1 was used for meta-analysis.</p><p><b>RESULTS</b>Three RCTs totaling 851 patients were included. The results showed that bone morphogenetic protein had no significant differences in fracture healing [RR = 1.16, 95% CI (0.95,1.41), P = 0.15], but lower secondary interventions incidence rate [RR = 0.72, 95% CI (0.58, 0.89), P = 0.003]. There were no significant differences between the two groups in the incidence of adverse events of infection [RR = 1.31, 95% CI (0.94, 1.81), P = 0.11] and pain [RR = 0.92, 95% CI (0.79, 1.08), P = 0.30].</p><p><b>CONCLUSION</b>Bone morphogenetic protein has certain advantages in treating open tibial fractures. It needs more high-quality articles to assess the long-term effect of different courses of treatments. The above conclusion still needs more high-quality randomized controlled trails to be verified owing to the limitations of the number and quality of systematic review included studies.</p>


Assuntos
Adulto , Feminino , Humanos , Masculino , Proteínas Morfogenéticas Ósseas , Usos Terapêuticos , Ensaios Clínicos Controlados Aleatórios como Assunto , Fraturas da Tíbia , Tratamento Farmacológico
14.
Indian J Biochem Biophys ; 2010 Dec; 47(6): 348-352
Artigo em Inglês | IMSEAR | ID: sea-135286

RESUMO

A strain F1 with high cellulase activity obtained from the deadwood stack was characterized as Ceriporia lacerate by examination of the general taxonomical characteristics and phylogenetic sequence analysis of rDNA ITS gene. The endoglucanase (EG) and filter paper cellulase (FPase) activities of the strain showed remarkable stability in the pH range of 4.0-7.0, and maintained about their maximal value of 76% and 50% after incubation at 70˚C for 6 h respectively. The strain grew particularly well with CMC-Na (1.0%) and yeast extract (0.4%) at 28˚C (pH 6.0) in flasks stirred at 150 × g for 6 days. Based on the thermostability and pH stability of cellulase, the strain appears to have potential in industrial applications and bioresource utilization.


Assuntos
Biocombustíveis , Celulase/metabolismo , China , Coriolaceae/genética , Coriolaceae/isolamento & purificação , Coriolaceae/metabolismo , Estabilidade Enzimática , Concentração de Íons de Hidrogênio , Lignina/metabolismo , Filogenia , Madeira/microbiologia
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