RESUMO
Objective: To investigate the clinical and pathological features and imaging manifestations of SFT (solitary fibrous tumor), and further to define the differiciation between the benign and malignant SFTs. Methods: The imaging findings were retrospectively analyzed and compared with the corresponding pathological results in 18 patients with SFT confirmed pathologically. Results: Of the 18 patients, 2 had postoperative recurrent or metastatic tumor, 3 had malignant SFT. The X-ray and MSCT (multi-slice computed tomography) scan images showed oval or lobulated masses with discrete margins except one malignant tumor. The tumor density was clear or nearly uniform. MRI (magnetic resonance imaging) examination showed that the tumors had intermediate signal intensity on T1WI (T1-weighted image) and heterogeneous signal intensity with flow voids on T2WI (T2-weighted image). All tumors showed heterogeneously intermediate or intense enhancement with geographic pattern. Intralesionally and paraleisonally prominent feeding vessels could be seen. The results of immunohistochemistry demonstrated that CD34 was positive in 18 patients; Bcl-2 and vimentin were positive in 17 patients; S100 was negative in 15 patients; cytokeratin and desmin were negative in 18 patients; Ki-67 expression was less than 5% in 15 benign tumors and more than 5% in 3 malignant tumors. Conclusion: There are some specific imaging features which are helpful to the differential diagnosis for SFT. These specific imaging features include the rich feeding vessels, the signal intensity on T2WI and the different enhancements associated with the tissue compositions of the tumor. However, making a definitive diagnosis still depends on pathology and immunohistochemistry. Copyright © 2013 by TUMOR.
RESUMO
Objective: Rabbit VX2 hepatoma was treated with transcatheter hepatic artery infusion with recombinant human (rh) endostatin combined with transcatheter arterial chemoembolization (TACE). The therapeutic efficacy was evaluated and the peri-cancerous CT perfusion features as well as the expressions of microvascular density (MVD) and vascular endothelial growth factor (VEGF) were analyzed. Methods: Thirty rabbits with VX2 hepatoma were randomly divided into three groups with 10 rabbits in each group. Group A were treated with TACE and infused with rh-endostatin via hepatic artery. Group B were treated with TACE only. Group C were control group. Routine CT scanning was performed before therapy and CT perfusion imaging were performed at 2nd weeks after treatment to get the data of blood flow (BF), blood volume (BV) and capillary permeability surface (PS) area. The rabbits were sacrified immediately after scanning. The MVD and VEGF expressions in tumor tissue slides were detected by immunohistochemistry. Results: The hepatoma growth rate was significantly lower in group A and B than that in group C (P 0.05). The expression of MVD positively correlated with the expression of VEGF in linear dependency (P 0.05). Conclusion: The combination therapy of TACE and administration of recombinant human endostatin via hepatic artery infusion significantly slows down the growth speed of hepatoma and inhibits tumor angiogenesis. The parameters of CT perfusion imaging can not reflect the changes of pathological parameters such as MVD and VEGF at any therapeutic condition.
RESUMO
<p><b>OBJECTIVE</b>To observe clinical therapeutic effect of acupuncture in abatement of fever.</p><p><b>METHODS</b>Eighty-six cases of high fever were randomly divided into two groups, an acupuncture group (n = 45) treated with acupuncture at Dazhui (GV 14) and a drug group (n = 41) treated with intramuscular injection of Antongding Injectio. Changes of body temperature before and after 24 hours treatment were observed by single blind.</p><p><b>RESULTS</b>In the acupuncture group, 9 cases were cured, and in the drug group, 2 cases were cured, the acupuncture group was better than the drug group in abatement of fever.</p><p><b>CONCLUSION</b>Acupuncture has a reliable therapeutic effect on fever.</p>