Insomnia and executive functions performance / 中华行为医学与脑科学杂志

The diagnosis of insomnia includes not only complaints of dissatisfaction with sleep quantity or quality, but also accomplished with daytime dysfunction.Cognitive impairment is one of the daytime dysfunction that insomnia patients often complain about, but the objective measures of cognitive function have no obtained consistent results.Executive functions consist of three core areas, including inhibitory control, working memory and cognitive flexibility.Executive functions represent advanced cognitive processes and are related to daily activities and academic achievement.Executive functions are sensitive to insufficient sleep.However, the relationship between insomnia and executive functions has not attracted enough attention, and it is unclear whether insomnia is related to impairment of executive functions.This article reviews the influence of insomnia on executive functions.The potential mechanism and the role of hyperarousal on executive functions impairment in patients with insomnia is also discussed.

The role of actigraphy in monitoring sleep and sleep disorders / 生物医学工程学杂志

The use of actigraphy, which can be used to estimate sleep-wake patterns from activity levels, has become common in sleep research. Actigraphy is a simple, cost-effective and non-invasive method for healthcare providers and researchers to assess patients sleep quality and screen for potential sleep disorders in recent years. But, there is no wide recognition and application of actigraphy in China up till now. This review summarized the application of actigraphy in evaluation of sleep and diagnosis of sleep disorders.

Advancement and the value of targeted gene related to lung cancer / 国际肿瘤学杂志

The occurrence and development of lung cancer are closely related to gene expression and mutations.Recent studies of lung cancer related genes show that the expression of COPS3 gene may play a key role in the lung cancer cell proliferation.Echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase fusion gene and epidermal growth factor receptor mutations coexist.GA733 gene is closely related to lung cancer survival.Fibroblast growth factor receptor 1,high mobility protein family,members of the scavenger receptor class 5 and epidermal growth factor receptor provide new ideas for targeted therapy of lung cancer.For the therapy of lung cancer,multiple gene therapy and gene therapy combined with conventional treatment is required.