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Journal of Southern Medical University ; (12): 79-81, 2006.
Artigo em Chinês | WPRIM | ID: wpr-234191

RESUMO

<p><b>OBJECTIVE</b>To propose the clinical classification of Peutz-Jeghers syndrome (PJS).</p><p><b>METHODS AND RESULTS</b>Retrospective analysis of 52 patients with PJS admitted in Nanfang Hospital from 1980 to 2003 was conducted. Twenty-four patients were found to have family history of PJS, who had a mean age of 19 years. In the PJS patients, the incidence of gastric polyps was 64.4%, colorectal polyps 76%, and small bowel polyps 95%. The number of polyps was above 50 in 19 of the 31 patients with gastric polyps, in 18 of the 38 patients with colorectal polyps, and in 8 of the 19 patients with small bowel polyps. The pathology of the majority of the polyps (63/108) was characterized by hamartomas, and the incidence of malignancy was 13.5% in the PJS patients.</p><p><b>CONCLUSIONS</b>PJS can be classified according to family history and location, pathology, and number of the polyps. As most patients with over 50 polyps require surgical intervention, 50 polyps is recommended as the criteria for PJS classification. Endoscopic surgery may suffice for management of patients with fewer polyps (<50), while in patients with more polyps or small bowel polyps, open surgery combined with intraoperative endoscopic surgery is recommended.</p>


Assuntos
Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pólipos Intestinais , Patologia , Síndrome de Peutz-Jeghers , Classificação , Patologia , Cirurgia Geral , Estudos Retrospectivos
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