Lack of awareness and knowledge among people with scabies in a questionnaire based cross sectional and observational study

Background: Scabies awareness can decrease the disease health burden. The objective was to assess the awareness and knowledge among people with scabies in a questionnaire based cross sectional, observational study.Methods: Study was questionnaire based, cross sectional, descriptive study. 200 consecutive patients with scabies were enrolled for it.Results: Of the 200 participants, 125 (62.5%) were males and 75 (37.5%) were females. People of all educational levels were affected from scabies ranging from illiterate 25 (12.5%) to graduates 44 (22%). 95 (47.5%) participants did not knew that itching can be because of scabies. 171 (85.5%) participants had no idea of mode of spread of the disease. 199 (99.5%) participants had no knowledge of treatment. None of the participants knew that scabies is preventable.Conclusions: There is a general lack of awareness and knowledge among the people regarding various aspects of scabies. Increased health awareness programmes with more educational and psychosocial support should be provided to the people. Mass drug treatment of scabies in the area should be provided instead of treating the individual patients

Six-Minute Walk Test Outcomes in Patients with Diffuse Parenchymal Lung Disease

The 6-minute walk test (6MWT) is used to measure exercise capacity and assess prognosis in diffuse parenchymal lung disease (DPLD). Although the 6MWT is usually considered to be a test of submaximal exercise capacity in DPLD, the physiological load imposed by this test is not well described and 6MWT outcomes are poorly understood. This study aimed to compare cardiorespiratory responses to 6MWT in people with DPLD. Methods: An observational crosssectional study was carried out in a single tertiary care center in northern India which included 50 consecutive subjects (age >12 years) who had diffuse parenchymal lung diseases. In this study, the clinical, radiological and histological data subjects was collected. 6MWT was done of all the patients and results tabulated. Result: Desaturation on 6MWT (SPo2 <88% or fall of 4% from baseline) were seen in total of 33(66%) patients with most cases being IPF in which 17 patients (89.47%) out 19 cases showed desaturation. This was followed by NSIP with 4(67%) of of 6 cases and CTD-ILD having 7(53.8%) out of 13 cases showed desaturation. More studies are required from developing countries to ascertain the spectrum of DPLDs in different geographic. Conclusion: On average, the 6MWT elicits a high but submaximal oxygen uptake in people with DPLD. Fibrosis is associated with maximum destauration in 6MWT. However the physiological load varies between individuals, with higher peak VO2 in those with more severe disease that may match or exceed that achieved on CPET. The 6MWT is not always a test of submaximal exercise capacity in people with DPLD.

Clinicoradiological Profile of Patients with Diffuse Parenchymal Lung Disease

The profile of diffuse parenchymal lung disease (DPLD) has mainly been reported from the developed countries; the prevalence and outcome of DPLD is not studied well across India. The aim of this study is to describe the clinical radiological spectrum of various DPLDs from a tertiary care centre of a developing country. Methods: An observational cross-sectional study was carried out in a single tertiary care center in northern India which included 50 consecutive subjects (age >12 years) who had diffuse parenchymal lung diseases. In this study, the clinical, radiological and histological data subjects was collected. Results: Out of the total 50 subjects, mean age was 49.04 years with females constituting 58% of the total. Most common symptoms were gradually progressing dyspnoea (100%) followed by dry cough (76%). The commonest finding on chest radiograph in our series was reticular pattern (78%).The commonest pattern on high-resolution computed tomography was traction bronchiectasis (56%), followed by honeycombing (50%), septal thickening (46%).The commonest cause of DPLD in study was Idiopathic Pulmonary Fibrosis (38) %, followed by connective tissue – interstitial lung disease (CTD-ILD)(26%) and NSIP(12%). Smoking was one of the major risk factor associated with IPF, and 52.6% of patients with IPF were smokers (P<0.001). Conclusion: IPF (38%) was the commonest DPLD seen followed by CTD- ILD and NSIP at a tertiary center in northern India similar to the spectrum reported from developed countries. More studies are required from developing countries to ascertain the spectrum of DPLDs in different geographic

Clinicoradiological Profile of Patients with Connective Tissue related Diffuse Parenchymal Lung Disease

Diffuse Parenchymal Lung Disease (DPLD) is one of the most serious pulmonary complications associated with connective tissue diseases (CTDs), resulting in significant morbidity and mortality. Although the various CTDs associated with DPLD often are considered together because of their shared autoimmune nature, there are substantial differences in the clinical presentations and management of DPLD in each specific CTD. Methods: An observational crosssectional study was carried out in a single tertiary care center in northern India which included 50 consecutive subjects (age >12 years) of DPLD and amongst them patients having connective tissue diseases associated DPLD (CTD)-DPLD were studied.In this study, the clinical, radiological data of the subjects was collected. Results & Conclusion: Out of 50 patients, 13 patients turned out to be CTD-DPLD. The most common of these was Rheumatoid arthritis (53.8%) followed by Systemic sclerosis (38.4%) and sjogresn syndrome (7.7%). The average age in CTD-DPLD came out to be 47.8 years as opposed to 49.04 in DPLD patients. The average age in RA was 58.6 years, Systemic sclerosis was 40 years and Sjogrens syndrome was 45 years. Majority (92.3%) were females.

Epidemiology and outcome of burns at Khyber teaching hospital Peshawar

To determine the epidemiology, describe the clinical presentation, outcome and the factors responsible for fatal outcome of burn patients. A total of 240 patients admitted in Surgical D unit, Khyber Teaching Hospital, Peshawar from March 2004 to Feb 2005 with burn injuries were included. Patient characteristics including age, sex, type of burn, total body surface areas [TBSA] burned, any first aid received, treatment given in hospital and outcome were recorded. 52.2% of the 240 patients were females. 31.66% patients were below 10 years of age, while 21.25% and 27.08% were in the second and third decades. Majority had less than 20% TBSA burns [47.5%] and only 4.1% had more than 50% TBSA burns. Flame burns were the commonest [45%] followed by scalds 31.6% and electrical 10.83%. Scalds were common in children. 130 patients improved with daily washes, dressing and debridements, systemic and local antibiotics. Skingrafts needed in 30 patients, 36 were referred to plastic surgery unit and 16 with more than 40% TBSA burns were referred to specialized burn centres. Mortality was 19 with sepsis as the leading cause, multiple organ failure, and shock were other causes of mortality. Burns injury is a major public health concern and is associated with significantly high morbidity and mortality. Flame, scald and electrical burns are commonly a result of domestic and occupation accidents and are preventable. The effectiveness of initial resuscitation, infection control and adequate surgical treatment improves short and long term outcomes