Proteins of the brain and body wall in larvae of Drosophila melanogaster.

Proteins of the brain and body wall cells of third instar larvae of Drosophila melanogaster have been examined by two-dimensional gel electrophoresis. Out of over 600 [ 35 S ]-labelled peptide spots seen in brain or body wall extracts, 517 were common to both; 61 spots were unique to brain and 66 unique to muscle. Glycoproteins were identified by soaking the gels in radioactive iodinated Concanavalin-A. Forty four Con-Α binding glycoproteins were identifiable in the brain and 41 in the muscle extracts. Out of these, 8 glycoproteins of the brain and 8 of muscles appear to be tissue-specific.