Malignant Solitary Fibrous Tumor of Tandem Lesions in the Skull and Spine

A Solitary Fibrous Tumor (Sft) Is A Rare Neoplasm Originated From The Pleura, But They Can Occur In A Variety Of Extrathoracic Regions. Although Many Cases Of Primary Sft Have Been Reported, There Are Extremely Rare Repots To Date Of A Malignant Sft In The Spine Or Skull. A 54-year-woman Visited Our Hospital Due To Low Back Pain And Both Leg Radiating Pain. Several Imaging Studies Including Magnetic Resonance Imaging And Computed Tomography Revealed Expansive Enhanced Lesions In The Occipital Bone, T8, S1-2, And Ilium, With Neural Tissue Compression. We Performed Surgical Resection Of The Tumor In Each Site, And Postoperative Radiosurgery And Chemotherapy Were Performed. However, After Six Months, Tumors Were Recurred And Metastasized In Multiple Regions Including Whole Spine And Lung. The Authors Report Here The First Case Of Patient With Malignant Sft Of Tandem Lesions In The Various Bony Structures, Including Skull, Thoracic Spine, And Sacral Spine, With A Rapid Recurrence And Metastasis. Although Malignant Sft Is Extremely Rare, It Should Be Considered In The Differential Diagnosis And Carful Follow-up Is Needed.

Kaposi's sarcoma of the oral cavity in renal transplanted patient; a case report

Kaposi's sarcoma was first descrided by Kaposi in 1872 as an idiopathic multiple hemorrhagic sarcoma. Its clinical features revealed to be erythematous red or purple macule started out, and developing into palpable dome-shaped nodules. Etiology is not defined to detail at present. Kaposi's sarcoma is classified to 4 categories; Classical, African, Epidemic and Transplant type. Epidemic or AIDS categories is found approximately 20 % of all AIDS and has strong predilection for head and neck region. The first case of Kaposi's sarcoma observed in patients with kidney transplants was reported in 1969. Kaposi's sarcoma now accounts for 5% of all tumors associated with transplanted patients and alteration of the immunosuppression may have played a key role in these recipients. The most common site of Kaposi's sarcoma in transplanted patients are extremities but rare in head and neck area. We report a case of Kaposi's sarcoma on the hard palate in the kidney transplantation patient.

Clinicopathologic Characteristics of Neuroendocrine Tumor of the Stomach

PURPOSE: Very few cases of neuroendocrine tumor of the stomach have been reported in Korea. The prognosis of gastric neuroendocrine tumors is known to be poorer than that of ordinary gastric carcinomas. The purpose of this retrospective study was to review the clinicopathologic features of seven cases of this unusual gastric tumor. METHODS: Excluding the tumor containing only sparse neuroendocrine differentiation, we resected 7 typical neuroendocrine tumors from January 1995 to December 1997 at Asan Medical Center; 2,346 gastric cancer patients were treated surgically during the same period. Average follow up period was 22.6 months. RESULTS: A typical well demarcated tumor margin was observed in four of the seven cases. The entire tumor was located on the distal stomach. Even when the tumor had deep ulcerations, the tumor cells had not infiltrated the serosal layer. Three cases showed recurrence of disease. All the recurrences were found in the liver within 12 months, and two of them, who were not indicated for chemotherapy, died within 10 months after diagnosis of recurrence. One patient with a recurrence was treated with systemic chemotherapy just after the diagnosis and was still alive after 29 months. CONCLUSION: Gastric neuroendocrine tumor frequently recurs the liver even in an early stage and especially when preoperative CEA is increased. We experienced a case of successful control of hepatic metastasis by using systemic chemotherapy.