RESUMO
An epidemic of hepatitis C virus occurred in plasmapheresis donors on Guan county in 1985. Early on 1986, there were investigated the state of hepatitis C virus and hepatitis B virus infection in plasmapheresis and whole blood donors from the villages with plasmapheresis donation in that year 1985, the villages with five-year plasmapheresis donation and the villages bacially without blood donation, then the follow-up survey of them was made in 1990. The positive rates of anti-HCV for plasmapheresis donors in 1986 and 1990 were 64.7% and 43.9% respectively. The positive rates of anti-HCV in the plasmapheresis donors with abnormal ALT were 77.5% and 81.1% and in the plasmapheresis donors with normal ALT were 51.3% and 34.3%. The positive rate for anti-HCV in plasmapheresis donors was higher than that in the whole blood donors and controls. It was proposed that the increasing of anti-HCV screening in blood supplying villages was imperative. In addition, the follow-up survey of 91 anti-HCV positive plasmapheresis donors was made in the fifth year since then, the rate at which the positive results turned to negative was 30.8%, about 70% cases turned out to chronic.