Traditional Chinese Medicine Syndromes in Depressive Episodes of Bipolar Disorder Based on Cluster Analysis and Bayesian Network：A Cross-sectional Study / 中医杂志

ObjectiveTo explore the elements， distribution and characteristics of traditional Chinese medicine （TCM） syndromes in depressive episodes of bipolar disorder （BD）. MethodsBasic information， along with the four examination information， the Hamilton Depression Scale and Young Mania Rating Scale scores， were collected from 293 outpatients with BD at Beijing Anding Hospital， Capital Medical University. The four examination information with an occurrence rate greater than 12% were retained. The R language “dist” function was used to calculate the distances between samples using the Euclidean distance method. The hierarchical clustering of the four examination information was performed using the “hclust” function and the squared Euclidean distance method. A team of five researchers was formed to determine the nature and location of the essential elements of TCM syndrome in BD based on the clustering results. The PC algorithm was used to construct a Bayesian network model of the essential elements. The working group combined the essential elements of TCM syndromes in the Bayesian network according to the reference model results， and then extracted common TCM syndromes. The score of each patient based on the essential elements was matched with the common TCM syndromes to determine the syndrome type of each patient. The working group then performs conformity and revision based on this， obtaining the final distribution of TCM syndromes for the patients. ResultsThere were 77 common TCM symptoms in BD with a frequency greater than 12%. The top 15 symptoms with higher frequencies were slippery pulse， mental fatigue and lack of strength， wiry pulse， excessive rumination， preference for solitude， vexation， agitation and irritability， dry mouth， palpitations， profuse dreaming， unwarranted worries， chest oppression， thin white coating， amnesia， frequent sighing， and poor appetite. TCM syndrome elements of BD can be grouped into 11 categories. The nature of disease-related essential elements included fire， qi deficiency， blood deficiency， qi counterflow， yin deficiency， dampness， heat， fire from constraint， and phlegm. The location of disease-related essential elements included heart， liver， spleen， stomach， kidney， bladder channel， and gallbladder. By constructing a Bayesian network model and considering the opinions from the experts， six common syndromes of BD were identified， among which the highest proportion was heart-stomach heat accumulation， accounting for 27.99% （82 cases）， followed by heart-spleen deficiency （55 cases， 18.77%）， non-interaction between the heart and the kidney （49 cases， 16.72%）， liver constraint and blood deficiency （42 cases， 14.33%）， heart qi deficiency （37 cases， 12.63%）， and damp-heat in the liver and gallbladder （28 cases， 9.56%）. ConclusionsThe nature of disease-related elements of BD are predominantly fire and heat， while the location of disease-related essential elements are primarily associated with the heart， liver， and spleen. The most common TCM syndromes are heart-stomach heat accumulation and heart-spleen deficiency.

Discussion on the Function of Building a New Method of Syndrome Differentiation and Treatment by Thinking of Imagine——the Function of Syndrome Differentiation and Treatment by Wu Shen Zang / 世界科学技术-中医药现代化

Psychiatric disorders with the chief feature of psychiatric symptoms are different from body diseases, traditional syndrome differentiation and treatment of Zang and Fu based on somatic symptoms is not adapted to the psychiatric clinical practice, so the new method of syndrome differentiation and treatment should be established. The new method must be guided by the methodology of Chinese Medicine (CM) . Thinking of imagine is the core of CM, and formation of the CM theory and syndrome differentiation and treatment of clinical course also reflect this thinking model.The new method of syndrome differentiation and treatment based on psychiatric symptoms must be guided by the methodology of thinking of imagine, so this paper discussed the significance in establishing the new method of syndrome differentiation and treatment based on psychiatric symptoms from the methodology of thinking of imagine, and this paper perhaps provided an idea for the establishment of syndrome differentiation and treatment of psychiatric disorders.

Research Progress in the Treatment of Taucette Syndrone by Traditional Chinese Medicine / 中国药师

The pathogenesis of tourette syndrome is not clear yet, and the clinical manifestations are diverse. With modern medi-cal treatment, adverse reactions occur frequently in clinics. Based on syndrome differentiation, TCM treatment can well control the clinical symptoms of children, and achieve better results without obvious adverse reactions. TCM treatment has unique advantages. In the paper, the etiology and pathogenesis, and the classification of the disease were discussed, so as to systematically explore TCM treatment of the disease and provide reference for TCM treatment of the disease.

Reutilization of old crown of base tooth after its breaking / 重庆医科大学学报

Objective; To explore a new method and its clinical significance of restorative ceramo - metal by using cast metal post -core to reutilize the broken crown. Methods; 30 teeth were restored with ceramo - metal tooth by using cast metal post - core in order to preserve the old broken base tooth, and their prognoses were observed. Results: 30 teeth post - core were inserted smoothly, and PFM crowns border sealed. During 5 years follow up ,93% (28 teeth) cases were successful, although unfortunately there were 2 cases of failure with split of tooth root. Conclusion; Restoration of ceramo - metal tooth by cast metal post - core in order to reutilize the broken crown of the base tooth is convenient ,time - saving and well casted ,therefone it could be used widely in clinic.

The clinical Study in the use of the retainer in pulp chamber in the defect of the molar / 重庆医科大学学报

Objective:According to observe the 5-year clinical effect in the treatment of restoration of teeth with extensive de- fection through pulp chamber retainer,to discuss the usage and the defect of pulp chamber retainer.Methods:108 extensively damaged molars which had been finished pulp treatment were choosed.Retainers were fabricated correspond to the pulp chamber then full crow were factured.Results:108 molars were restored by full crown restoration with pulp chamber retainer,in which only 7 cases fell off.Conclusion:The retainer in pulp chamber can be used in the treatment of teeth with extensice defection and makes it easier in clinical operation.

The masticatory efficiency of the metals porcelain prostheses restoration for severe tooth wear / 重庆医科大学学报

Objective:To explore a new method and it's clinical efficiency of porcelain technique on severe tooth wear and dentition defect.Methods:The transitional occlusal pad restored the vertical dimension and centric relation.decreased TMD symptoms.The porcelain technique was used to reconstruct the occlusal relationship,their prognoses and patients' satisfactory were recorded.Results:45 patients suffered from serious dental abrasion,whose clinical symptoms got much better and masticatory efficiency improved significantly.Conclusion:Porcelain is an aesthetic and comfortable technique to improve patients' masticatory efficiency significantly which is similar to real tooth.