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1.
Korean Journal of Anesthesiology ; : 312-317, 2006.
Artigo em Coreano | WPRIM | ID: wpr-135528

RESUMO

BACKGROUND: Combination of propofol and remifentanil is an ideal regimen for total intravenous anesthesia. The purpose of this study is to determine the effect-site concentration of remifentanil for prevention of hemodynamic responses to tracheal intubation during fixed propofol infusion (4microgram/ml) and to find any sexual differences. METHODS: Thirty ASA physical status I-II patients undergoing general anesthesia were assigned to male (n = 15), and female (n = 15) group. All patients received a target controlled infusion (TCI) of propofol with a fixed effect-site concentration of 4microgram/ml. After target effect-site concentration of propofol and remifentanil was reached, tracheal intubation was performed. The hemodynamic changes (systolic/diastolic blood pressure, mean arterial pressure, and heart rate) were measured at 1 and 2 min before tracheal intubation (baseline), immediately after, 1, 2, 3, 4 and 5 min following tracheal intubation. In both groups, effect-site concentration of remifentanil was initiated with 3 ng/ml. Subsequent concentration of remifentanil was determined by hemodynamic responses of the previous patient to tracheal intubation based on up and down sequential allocation. RESULTS: The mean EC50 of remifentanil for prevention of hemodynamic responses to tracheal intubation were 1.37 ng/ml (95% CI, 0.95-1.81 microgram/ml) in male group and 1.05 microgram/ml (95% CI, 0.68-1.40 ng/ml) in female group, respectively. In addition, there were no statistical significant differences between two groups. CONCLUSIONS: Relatively small dosages of remifentanil (0.68-1.81 microgram/ml) for attenuation of hemodynamic responses to tracheal intubation was needed in Korean population in propofol TCI and there were no sexual differences.


Assuntos
Feminino , Humanos , Masculino , Anestesia Geral , Anestesia Intravenosa , Pressão Arterial , Pressão Sanguínea , Frequência Cardíaca , Coração , Hemodinâmica , Intubação , Propofol , Caracteres Sexuais
2.
Korean Journal of Anesthesiology ; : 312-317, 2006.
Artigo em Coreano | WPRIM | ID: wpr-135525

RESUMO

BACKGROUND: Combination of propofol and remifentanil is an ideal regimen for total intravenous anesthesia. The purpose of this study is to determine the effect-site concentration of remifentanil for prevention of hemodynamic responses to tracheal intubation during fixed propofol infusion (4microgram/ml) and to find any sexual differences. METHODS: Thirty ASA physical status I-II patients undergoing general anesthesia were assigned to male (n = 15), and female (n = 15) group. All patients received a target controlled infusion (TCI) of propofol with a fixed effect-site concentration of 4microgram/ml. After target effect-site concentration of propofol and remifentanil was reached, tracheal intubation was performed. The hemodynamic changes (systolic/diastolic blood pressure, mean arterial pressure, and heart rate) were measured at 1 and 2 min before tracheal intubation (baseline), immediately after, 1, 2, 3, 4 and 5 min following tracheal intubation. In both groups, effect-site concentration of remifentanil was initiated with 3 ng/ml. Subsequent concentration of remifentanil was determined by hemodynamic responses of the previous patient to tracheal intubation based on up and down sequential allocation. RESULTS: The mean EC50 of remifentanil for prevention of hemodynamic responses to tracheal intubation were 1.37 ng/ml (95% CI, 0.95-1.81 microgram/ml) in male group and 1.05 microgram/ml (95% CI, 0.68-1.40 ng/ml) in female group, respectively. In addition, there were no statistical significant differences between two groups. CONCLUSIONS: Relatively small dosages of remifentanil (0.68-1.81 microgram/ml) for attenuation of hemodynamic responses to tracheal intubation was needed in Korean population in propofol TCI and there were no sexual differences.


Assuntos
Feminino , Humanos , Masculino , Anestesia Geral , Anestesia Intravenosa , Pressão Arterial , Pressão Sanguínea , Frequência Cardíaca , Coração , Hemodinâmica , Intubação , Propofol , Caracteres Sexuais
3.
Korean Journal of Anesthesiology ; : 500-502, 2001.
Artigo em Coreano | WPRIM | ID: wpr-35404

RESUMO

A stellate ganglion block is frequently used in the pain clinic. It has been known that a stellate ganglion block maintains the homeostasis of hormones by improvement of blood supply to the brain. Therefore it has a systemic effect as well as a regional effect. Androgen, the sebaceous gland, hair follicle and bacteria are involved in pathogenesis of acne. The background for the treatment of acne with a stellate ganglion block can be related to the increase of blood supply to the face and the effect on the pineal gland. We administered a stellate ganglion block for the treatment of acne and had good results. From our experience, we consider a stellate ganglion block as the one of the effective treatment of acne.


Assuntos
Acne Vulgar , Bactérias , Encéfalo , Folículo Piloso , Homeostase , Clínicas de Dor , Glândula Pineal , Glândulas Sebáceas , Gânglio Estrelado
4.
Korean Journal of Anesthesiology ; : 169-174, 2001.
Artigo em Coreano | WPRIM | ID: wpr-161351

RESUMO

BACKGROUND: Tracheal intubation is usually carried out under a combination of general anesthesia and muscle relaxation. Recent sutdies have found satisfactory conditions for intubation of the trachea without using muscle relaxants. However, these studies have used large amounts of propofol or expensive opioids like alfentanil and remifentanil. In this study, we evaluated intubation conditions and success rate with midazolam, fentanyl, propofol and either 10% lidocaine applied topically into the larynx and trachea or not. METHODS: Forty patients of ASA class I or II were randomly allocated to one of two groups. All patients received glycopyrrolate 0.2 mg, midazolam 0.03 mg/kg and fentanyl 2 mcg/kg IV before induction of anesthesia and propofol 2 mg/kg IV for induction of anesthesia. Group I patients (n = 20) received 10% lidocaine into the larynx and trachea topically, and group II patients (n = 20) did not. After loss of the eyelid reflex, laryngoscopy and endotracheal intubation were attempted and airway conditions were graded. The success rate of intubation was evaluated. RESULTS: Intubation without a muscle relaxant was possible in 19 of 20 (95%) patients in group I and 8 of 20 (40%) patients in group II. There were no significant differences in scoring criteria for various airway conditions such as jaw tone, vocal cord exposure and cord position. CONCLUSIONS: Induction of anesthesia with midazolam 0.03 mg/kg, fentanyl 2 mcg/kg and propofol 2 mg/kg combined with 2 ml of 10% lidocaine spray into the larynx and trachea offered a satisfactory success rate of intubation without muscle relaxants.


Assuntos
Humanos , Alfentanil , Analgésicos Opioides , Anestesia , Anestesia Geral , Pálpebras , Fentanila , Glicopirrolato , Intubação , Intubação Intratraqueal , Arcada Osseodentária , Laringoscopia , Laringe , Lidocaína , Midazolam , Relaxamento Muscular , Propofol , Reflexo , Traqueia , Prega Vocal
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