Acid-Base and Blood-Gas Status of Newborn Umbilical Blood according to Induction-Delivery and Uterine Incision-Delivery Intervals under General Anesthesia for Cesaeran Section / 대한마취과학회지

In cesarean section under general anesthesia, inhalation anesthetics may compound fetal acidosis brought by maternal hypoxia or uteroplacental insufficiency. The chance af fetal distress may be increased with prolonged induction-delivery (ID) and uterine incision-delivery (UD) intervals in such cases. These studies were undertaken to evaluate the changes of fetal acid-base and blood-gas status according to these intervals in 58 parturients given cesarean section under general anesthesia. 58 neonates were divided into three groups according to their ID interval [group 1 (N=26): less than 6 minutes, group 2 (N=25): 6 to 10 minutes, group 3 (N=7): 10 to 15 minutes] and four groups according to their UD interval[group A (N=25): less than 60 seconds, group B (N=22): 60 to 90 seconds, group C (N=9): 90 to 120 seconds, group D (N=2): 120 to 180 seconds]. The pH, PCO2, PO2 and HCO3 values of the umbilical vein blood at delivery in the groups 1, 2, 3 divided according to ID intervals were 7.37+/-0.03, 7.36+/-0.04, 7.36+/-0.03; 39.75+/-4.83, 41.76+/- 4.03, 38.81+/-2.31; 34.35+/-745, 32.65+/-9.63, 30.89+/-11.28 (in mmHg); and 23.21+/-0.33, 23.30+/-0.26, 22.15+/-0.52 (in mEq/L), respectively, and in groups A, B, C, D divided according to UD intervals, they were 7.37+/-0.02, 7.37+/-0.02, 7.37+/-0.03, 7.36+/-0.06; 40.30+/-5.20, 40,63+/-3.11, 39.96+/-4.42, 40.03 +/-5.09; 32.35+/-8.23, 31.82+/-0.17, 35.67+/-8.35, 33.53+/-10.53 (in mmHg); and 23.14+0.26, 23.60+/-0.36, 22.88+/-0.67, 23.35+/-0.35 (in mEq/L), respectively. No significant differences in these values were present between these ID- or UD- based groups.

The Effect of Anesthetic Duration of Epinephrine and Morphine Mixture with Local Anesthetics Simultaneously on Spinal Anesthesia / 대한마취과학회지

The effect of anesthetic duration of epinephrine and morphine mixture with hyperbaric tetracaine on spinal anesthesia was studied at Tague Catholic University Hospital. Fifty-two pa- tients, ASA physical status I-II, were selected randomly and divided them into 4 groups as follows: Group A; Only 0.5% hyperbaric tetracaine 14 mg injection. Group B; Mixture of 0.5% hyperbaric tetracaine 14 mg and morphine 0.15 mg injection. Group C; Mixture of 0.5% hyperbaric tetracaine l4 mg and epinephrine 0.2 mg injection. Group D; Mixture of 0.5% hyperbaric tetracaine 14 mg, morphine 0.15 mg and epinephrine 0.2 mg injection. The results of motor block onset, motor block duration, sensory block onset and sensory block duration were as follows: 1) Motor block onset; There were no statistical differences between each groups. 2) Motor block duration; The duration of motor blocks were significantly longer in group C and D than group A. The duration of motor block was significantly longer in group D than group B. 3) sensory block onset; There were no statistical differences between each groups. 4) Sensory block duration, The duration of sensory blocks were significantly longer in group D than group A, B and C. These results suggested that the effect of anesthetic duration of epinephrine and morphine mixture with local anesthetics simultaneously on spinal anesthesia were more prolonged than tetracaine injeetion only and injection of tetracaine, epinephrine mixture.