Evaluation of the correlation between fetal well being tests with APGAR score and pH of umbilical artery in high risk pregnant women

Acidosis-hypoxic phenomenon is a valid indicator to determine fetal distress and is defined by mearuring the blood pH of umbilical cord. None of the present screening tests for evaluation of pregnant mothers have acceptable clinical accuracy to assess fetal acidosis. We decided to evaluate the relationshop between fetal well being tests Non-Stress Test [NST], Oxytocin Challenge Test [OCT] and Biophysical Profile [BPP] with APGAR score and the blood pH of umbilical cord. In this case-control study, we enrolled 50 high-risk pregnant women [BPP test positive, OCT positive or non reactive NST] as cases and 50 pregnant women without fetal risk factors as control group. The umbilical cord blood sample was taken immediately after delivery. Some variables such as maternal age, gestational age, parity, NST, OCT, BPP, blood pH of umbilical cord, neonatal weight, sex and APGAR score were evaluated and the data was analyzed by SPSS software. Discrimination between NST with acidosis [P<0.01] was significant in the case and control groups, but in case of OCT with acidosis it was not significant. NST and OCT had low sensitivity [58.3 and 46.5 respectively]. Besides, the relationship between BPP and blood pH of umbilical cord was significant in the case and control groups [P<0.02]. APGAR score of the cases were lower than the control group [P<0.0001]. In evaluation of fetal acidosis, the BPP test is the best screening test comparing to NST and OCT

[Effects of maternal body mass index and weight gain during pregnancy on the outcome of delivery]

Abnormal BMI of mother and weight gain play very important role in the outcome of pregnancy. Several researches were done on the correlation between body mass index [BMI] and mother weight gain in pregnancy, and the complications in neonates, like low birth weight and prematurity and mother complications like preeclampsia. This study was performed in order to determine the correlation between body mass index and weight gain during pregnancy, maternal and fetal complications in patient admitted to Deziani hospital in Gorgan, Iran. This cross-sectional study was done on 350 pregnant women in Deziani hospital during a year [2002-03]. Patients' information's like mother age, pre-pregnancy weight, weight gain during pregnancy and maternal-fetal complications [preeclampsia, PROM, preterm labor and macrosomia] were recorded. After coding, data were analyzed by SPSS and Chi-Square test was used for description. In high BMI women, higher weight gain was seen than normal BMI women. Preterm labor was significantly related with pre-pregnancy BMI [P<0.05] but no relationship was seen between weight gain and preterm labor. PROM and birth weight were significantly related to pre-pregnancy BMI and weight gain during pregnancy [P<0.05]. Preeclampsia has significant relationship with weight gain [P<0.05]; but not with pre-pregnancy BMI. Abnormal maternal pre-pregnancy BMI and weight gain during pregnancy can complicate the delivery. Low and high BMI and weight gain during pregnancy can contribute with the complications in mothers and neonates

[ relation between asymptomatic bacteriuria and preeclampsia]

Background and Objective: asymptomatic bacteriuria [ASB] is a significant problem during pregnancy because it can be developed into more severe infections that may have repercussions for the health of the mother and unborn child. The aim of this study was to assess relationship between asymptomatic bacteriuria and preeclampsia in Gorgan

Materials and Methods: this case control study performed on 150 preeclamptic women [Case group] compared with 150 healthy pregnant women [Control group] who hospitalized from 2002 to 2002 [Gravid, age and history of preeclampsia was matched with 2 group]. The questionnaires and checklist was completed, urine analysis, and urine culture were performed. The data analyzed with SPSS software and statistical descriptive and analytic such as: T-student, U-Mann Whitney

Results: the risk of preeclampsia in pregnant women with ABS was 3.2 fold to healthy pregnant women [OR=3.22, CI 95% for OR=1.99, 5.21]

Conclusion: asymptomatic bacteriuria may predisposing factor to preeclampsia, we suggest screening of ASB in the 1st prenatal care and follow in 2nd and 3rd trimester of pregnancy o prevent the main side effect in pregnancy and the safety of mothers