Hyperoxaluria and hyperuricosuria in calcium urolithiasis

Twenty four hour urinary oxalate and uric acid were determined in 139 calcium stone-formers and 100 control subjects. Hyperoxaluria [>41 mg/day] was found in 42 out of 139 stone-formers [30.2%]. Hyperuricosuria [>531.8 mg/day] was found in 19 out of 139 calcium stone-formers [13.7%]. It is concluded that hyperoxaluria and hyperuricosuria are common associated metabolic abnormalities in calcium urolithiasis

Idiopathic hypercalciuria in calcium urolithiasis

A study of 139 calcium stone-formers and 100 control subjects in the Suez Canal area revealed the presence of idiopathic hypercalciuria [24-hour urinary calcium >222 mg/24 hours] in 28 of them [20.1%]. Employing oral calcium loading test and nephrogenous CAMP level for the differentiation between absorptive [AHC] and renal [RHC] hypercalciuria, 19 [67.9%] had AHC and 9 [32.1%] had RHC. The relatively high incidence of IHC in this study alerts attention to disturbances in calcium metabolism as important associated abnormality in calcium urolithiasis and also to the value of calcium-loading lest for differentiating AHC from RHC for the sake of choice of selective lines of management