The script clinical reasoning test An internal medicine educational practice perspective

One of the main skills in internal medicine is clinical decision making. To make clinical decisions, physicians in training reorganize their knowledge in order to optimally perform their clinical functions (diagnosis, research methods and treatment), which are organized according to disease scripts. This ability develops with experience and is acquired during their academic training. The script concordance test has been described as an innovative evaluation tool, designed to evaluate clinical decision making (clinical reasoning) in addition to the degree of knowledge. The script theory, understood as the organization of knowledge, is the basis for decision making. Disease scripts play a key role in supporting and developing clinical reasoning skills, which should be acquired in order to produce differential diagnoses and interpret clinical data. (Acta Med Colomb 2022; 48. DOI:https://doi.org/10.36104/amc.2023.2569).

Criptococosis y linfocitopenia T CD4 idiopática: Reporte de un caso / Cryptococcosis and idiopathic CD4 T lymphocytopenia: A case report

Resumen La linfocitopenia T CD4 idiopática (LCI) es un síndrome clínico inusual que se caracteriza por un déficit de células T CD4+ circulantes en ausencia de infección por VIH u otra condición de inmunosupresión. Los pacientes con dicha enfermedad pueden presentarse asintomáticos o con infecciones oportunistas, las más frecuentes son por criptococo, micobacterias o virales como herpes zoster. Presentamos el caso de un hombre de 32 años, sin antecedentes, en quien se descartó infección por retrovirus, con recuento de linfocitos T CD4+ menor a 300 células/m3; se diagnosticó LCI posterior al diagnóstico de criptococomas cerebrales mediante hallazgos imagenológicos los cuales fueron congruentes con estudios microbiológicos.

Summary Idiopathic CD4 T lymphocytopenia (ICL) is an unusual clinical syndrome characterized by a deficit of circulating CD4 + T cells in the absence of HIV infection or another immunosuppression condition. Patients with this disease may present asymptomatic or with opportunistic infections, the most frequent are cryptococcus, mycobacteria or viral such as herpes zoster. We present a case of a 32-year-old man with no prior disease, in whom retrovirus infection was discarded, with CD4 + T lymphocyte count less than 300 cells/m3; ICL was diagnosed after the diagnosis of brain cryptococomas by imaging findings which were consistent with microbiological studies.