Plasma adhesion molecules levels in patients with chronic heart failure

This study was done on 30 male patients suffering from chronic heart failure. Fifteen patients have previous history of ischemic heart. Their ages ranged from 45 to 55 years and 15 patients with past history of rheumatic heart, their ages ranged from 45 to 55 years. Another 10 normal healthy volunteers were taken as control with ages ranged from 45 to 55 years. Plasma VCAM-1, ICAM-1 and TM were measured. Serum C-reactive protein [CRP] and erythrocyte sedimentation rate [ESR] were also measured in both patients and controls. There were significant increases in all parameters if compared with those of normal individuals. This indicated that plasma adhesion molecules were increased in patients with chronic heart failure of different causes