RESUMO
Background and Objectives: Several studies have showed that high levels of CRP and homocysteine increase the risk of coronary artery diseases. This study was aimed to investigate the effects of combined exercises on homocysteine, CRP and lipid profile in middle-aged inactive men
Materials and Methods: In this semi-empirical study, 24 subjects were selected by convenience sampling method. The cases were randomly assigned into two groups [experimental [n=12] and control [n=12]]. The aerobic training method included: 3 times a week, 20 minutes per session, with intensity of 60-70 percent of heart rate reserve. Also the resistance training program conducted by intensity of 70% one repetition maximum
Results: The levels of serum homocysteine and CRP after combined exercises were decreased significantly [P=0.001 and P=0.003, respectively]. Although, TC, TG, HDL-C and LDL-C levels between both groups did not differed significantly. As well as, maximum oxygen consumption has increased significantly [P=0.008]
Conclusion: It seems that combined exercise [aerobic and resistance] with reduction of homocysteine and CRP levels can used as a non-pharmacological methods to prevent the development of atherosclerosis
RESUMO
Background: The risk of developing diabetes and cardiovascular disease in the elderly, obese and sedentary population is high. Exercise can improve metabolic disorders associated with these diseases. The aim of this study was to investigate the effect of eight weeks resistance exercises on C-reactive protein [CRP], Interleukin-6 [IL-6] and lipid biomarkers in sedentary middle-aged men.
Materials and Methods: This quasi-experimental study was conducted in 2012 in the city of Sari. In this study, 24 subjects were randomly divided into two groups; experimental and control group [each group 12]. The resistance exercise program was performed for eight weeks, 3 times a week, 90 minutes per session, with intensity of 60-70 one repetition maximum. Blood samples were collected before and after the exercise intervention. Data were analyzed using SPSS version 15 and P<0.05 was statistically considered significant.
Results: The results showed that in the resistance exercise group, CRP, IL-6 and percent body fat decreased by 19.14%, 11.00% and 9.55%, respectively [P<0.05]. Although, total cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol levels were unchanged in two groups [P>0.05].
Conclusion: Eight weeks resistance exercises, through decreasing CRP and IL-6 levels, two known new risk factors, can reduce atherosclerosis and be effective in cardiovascular health.