Neonatal cerebral color doppler duplex imaging in moderate hypoxic ischemic encephalopathy

The aim of this study was to evaluate the neonatal cerebral blood flow velocity changes in moderate hypoxic ischemic encephalopathy [HIE] using color Doppler duplex ultrasound. Fifteen full term asphyxiated newborn infants with moderate HIE were examined prospectively using transfontanel color Doppler duplex ultrasound with 5 mHz curvilinear probe. Fifteen full term age and weight matched healthy newborn infants were also examined as a control group. The results showed a significant reduction in the mean values of peak systolic velocity [PSV], end diastolic velocity [EDV] and mean flow velocity [MV] in anterior cerebral artery [ACA] in newborn infants with HIE than those of the control group. The PSV, EDV and MV values in middle cerebral artery [MCA] were significantly lower than that of the control group. Doppler duplex ultrasound is noninvasive imaging modality to evaluate cerebrovascular dynamics in newborn infants with HIE

Color duplex study in ocular Behcet's disease

The aim of this study was to evaluate the haemodynamic characteristics of ophthalmic vasculature of eyes with Behcet's disease. Both eyes of patients with Behcet's disease were evaluated and classified according to criteria recommended by International Study Group for Behcet's disease and after ophthalmological and fluorescein angiographic findings into 3 groups: Behcet's disease patients without ocular involvement, Behcet's disease patients with mild to moderate vasculitis and Behcet's disease patients with severe vasculitis. Color duplex was done to quantitate blood flow velocities and vascular resistance in the ophthalmic artery [OA], central retinal artery [CRA] and central retinal vein [CRV] of these patients and also group of healthy volunteers. All four groups were age and sex matched. In the OA, peak systolic, end diastolic and average flow velocities were significantly higher in patients with retinal vasculitis due to Behcet's disease than in patients with Behcet's disease but without ocular involvement and in control groups [P < 0.05]. CRA blood flow velocities of patients with severe retinal vasculitis were significantly lower than those with mild to moderate vasculitis, Behcet's disease without ocular involvement and control groups. Also, peak systolic and end diastolic velocities in CRA were significantly lower in patients with Behcet's disease without ocular involvement than in the control group. In the CRV, the average blood flow velocities of patients with severe vasculitis were significantly lower than in mild to moderate vasculitis, Behcet's disease patients without ocular involvement and control groups. Color duplex is a non-invasive, rapid and useful technique for assessing patients with Behcet's disease and permitting both quantitative and qualitative examination of the ophthalmic vascular system