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JPAD-Journal of Pakistan Association of Dermatologists. 2012; 22 (4): 312-314
em Inglês
| IMEMR
| ID: emr-155623
RESUMO
To assess the association between lichen planus and Helicobacter pylori. In this analytical, case-control study, 60 patients with lichen planus [confirmed by histopathology] and 60 age- and sex-matched volunteer blood donors were selected. Tests for H. pylori IgA and IgG antibodies were performed by ELISA. The mean age of patients was 36.3 +/- 12.6 years. Of 60 patients with lichen planus, H. pylori IgA antibodies were positive in 46 [76.6%] patients and in 18 [30%] controls [p=0.001]. Similarly, H. pylori IgG antibodies were positive in 55 [91.7%] patients of lichen planus and in 44 [73.3%] controls [p=0.007]. These findings suggest that H. pylori may be implicated in the etiology of the lichen planus