comparative study of immunoglobulins E,A,M,G, and eosinophilia in ascariasis and schistosomiasis

Serum Igs E, A, M, G, and blood eosinophils were determined in 31 helminth-infested subjects [ascaris 15, bilharzia 13, mixed infection 3]. A highly significant rise [4 times the control mean value] was obtained with IgE and eosinophils. The former was more elevated in ascariasis and vice versa. Correlation study suggests that the eosinophil response is not solely IgE-mediated. While IgA was significantly raised, IgM was raised in ascaris cases and the significant rise in IgG was more evident in bilharzial cases. cases with mixed infection revealed no summation effect. The wide range, in the pathological group was pointed out and the possible mechanism and meaning of the findings were discussed