Higher frequency of methicillin resistant bacteria in children with familial mediterranean fever

To investigate resistant microorganisms in nasal mucosa of children with Familial Mediterranean Fever. The study was conducted from March to May 2013 at Mustafa Kemal University, Turkey, and comprised children with Familial Mediterranean Fever and healthy controls. All subjects had no history of antibiotic or local and/or systemic steroid use within the preceding 2 weeks. Nasal swab samples were obtained from all the subjects. Strain identification was done by using standard methods. SPSS 13 was used for statistical analysis. Of the 151 subjects in the study, 73[48.34%] were cases and 78[51.65%] were controls. Among the cases, there were 26[35.6%] girls, while among the controls, there were 40[51.3%] girls [p=0.052]. The mean age of the cases was 7.78 +/- 3.34 years [range: 3-15 years], while it was 8.15 +/- 2.71 years [range: 3-16] among the controls [p=0.208]. Methicillin-resistant coagulase-negative staphylococcus and methicillin-resistant staphylococcus aureus were isolated in both the groups. The growth rate of resistant bacteria was 63% [n=46] in the cases, in the controls [p=0.003; odds ratio [OR]: 2.7; 95% confidence interval [CI]: 1.4-5.2]. Among the controls, history of hospitalisation increased the risk for the presence of resistant bacteria by 7.7 fold [OR: 7.7; 95% CI: 1.4 - 40.4]. Higher rates of resistant bacteria showed that they were at risk of comorbidities related to antibiotic resistance

Evaluation of Mean Platelet Volume values in lean women with polycystic ovary syndrome

Mean Platelet Volume [MPV] is an important indicator of platelet activation. It is known that MPV increases in patients with coronory artery disease, diabetes mellitus, atherosclerosis and Polycystic ovary syndrome [PCOS]. Our aim was to measure the MPV in lean patients with polycystic ovary syndrome. The present study was designed to examine the platelet function by measuring MPV in non-obese women with PCOS. A total of 50 outpatients with PCOS were included. The control group consisted of 50 healthy subjects. Serum platelet, MPV, and white blood cell [WBC] levels were compared and evaluated retrospectively in all participants. These values were compared by statistical analysis. There were no statistically significant difference in between groups regarding MPV [p=0.357], WBC [p=0.414] and platelet [p=0.666]. There are studies implying MPV increase in PCOS patients, in our patients MPV levels did not correlate with PCOS except for patients with obesity. We think that PCOS itself has no effect on MPV levels and obesity changes MPV levels