[ effect of eight week interval acute training on plasma visfatin, TNF-alpha and IL-6 in rats: a brief report]

Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Exercise training exerts beneficial effects on adipose tissue. However, less is known regarding visfatin's, IL-6 and TNF-alpha response to an interval acute training. Therefore, we investigated the effects of acute interval exercise on plasma visfatin, TNF-alpha and IL-6 levels, in healthy female rats. Furthermore, correlate between changes probably these factors were also assessed. This study was conducted experimentally. Forty five female sprague dawley rat were randomly divided into three groups: pre test [n = 15], treadmill exercise [n = 15] and sedentary controls [n = 15]. The acute alternative exercise consisted of treadmill running: 3 session/ week for 8 week. The changes of plasma IL-6, TNF-alpha and Visfatin levels were measured by ELISA analysis. Data were analyzed using analysis of variance with measures [ANOVA] and post hoc Tukey test. Acute interval treadmill exercise led to significant decreases in visfatin [P = 0/036], IL-6 [P = 0/009] and TNF-alpha [P = 0/022] plasma levels between the groups. Also, this study no significant correlations between the changes in adipokines were observed. Decreased levels of TNF-alpha and IL-6 correlated with intensity and duration exercise. Furthermore, probably there were some factors except weight decreasing that affects on visfatin decrease. Therefore, the reduction of this factor may cause in preventing metabolic disease

effects of three sessions of running on a negative slope on serum levels of liver enzymes in adult male rats

The purpose of this study was to investigate the effects of three sessions of running on a negative slope [eccentric contraction] on changes of the serum levels of aspartate aminotransferase [AST] and alanin aminotransferaze [ALT] in adult male rats. 20 adult male rats were divided randomly into two equal groups [exercise and control]. Levels of AST and ALT in both groups were measured in a fasting state, 24 hours before and 24 hours after the last session of training. Exercise increased the levels of serum AST and ALT enzymes, significantly [p<0.05]. Eccentric exercise, without allowing enough time for returning to the pre-exercise state, leads to the damage of some body organs such as the liver

Prevalence of overweight and obesity and their relation to hypertension in adult male population of Fars province of Iran

The prevalence of overweight and obesity is increasing in Iran since the last decade. Both are associated with high mortality and morbidity, including cardiovascular disease, diabetes mellitus, degenerative joint disease, gallbladder disease, depression and cancer. To estimate the prevalence of overweight and obesity and their relation to hypertension in adult population of Fars Province. A total of 401 adult males were included in the study, out of which 372 underwent all required tests. Body weight and height were measured by a scale and a non-stretchable tape respectively. Body mass index was calculated according to World Health Organization [2002] definition. Waist circumference and waist hip ratio were measured in a standing position. Body fat % was measured by Bioelectrical Impedance Analysis. The partial correlation coefficient was used to quantify the association between all anthropometric indicators with hypertension. Linear regression analysis was used to assess the influence of all anthropometric indicators on the variance of systolic and diastolic blood pressure. The mean body mass index was 26.12kg/m2, waist hip ratio was 0.93.7, waist circumference was 90.10cm and fat percentage was 25.2%. The mean systolic blood pressure was 130.78mmHg and diastolic blood pressure was 79.56mmHg. Eighty seven subjects [23.4%] had systolic blood pressure higher than cut-off value and 39 subjects [10.5%] had diastolic blood pressure higher than cut-off value. Descriptive analysis showed that 30.1% population was overweight and 13.7% were obese. Partial correlation for all the anthropometric indicators [waist- hip ratio, body mass index and % body fat] showed a positive correlation with both systolic blood pressure and diastolic blood pressure. Waist circumference only correlated with systolic blood pressure. Adult male population of Fars province had a high prevalence of hypertension, overweight and obesity which can be handled through healthy diet and physical exercises